Literature DB >> 27380124

Treatment of Children With Scalds by Xenografts: Report From a Swedish Burn Centre.

Moustafa Elmasry1, Ingrid Steinvall, Johan Thorfinn, Ashraf H Abbas, Islam Abdelrahman, Osama A Adly, Folke Sjöberg.   

Abstract

Scalds are the most common type of burn in children, and one way to treat them is with xenografts with no topical antimicrobials in line with the recommendations of a recent review. However, this treatment has not been examined in detail. Our aim was to describe the treatment of such children when biological dressings (xenografts) were used without local antimicrobials. We reviewed the medical records of all children admitted to a Swedish National Burn Centre during the period 2010-2012 with scalds who were treated with xenografts. Percentage TBSA injured, age, length of hospital stay, number of operations, antibiotics given, duration of antibiotic treatment, and pain score during the first 3 days, application of xenografts, and clinical notes of wound infection were recorded. We studied 67 children, (43 of whom were boys), with a median (interquartile range [IQR]) age of 1 (1-2) year and median (IQR) TBSA% 6.2 (4-11). Twenty children (30%) required operation. Twelve (18%) developed a wound infection, 29 (43%) had other infections, and 26 (39%) were free from infection. The median (IQR) duration of systemic antibiotics was 10 (6-13) days. On the day that the xenografts were applied 10 of the children had a Face, Legs, Activity, Cry, and Consolability (FLACC) score between 3 and 7, and during the following 2 days, only four children scored in this range. The remaining 57 children had scores < 3 on the day that xenografts were applied and on the following 2 days. Median (IQR) length of stay/TBSA% was 0.7 (0.4-1.0). Treatment with xenografts was associated with median length of stay/TBSA% <1 and low pain scores. Despite a high rate of prescription of systemic antibiotics, most were for reasons other than wound infection.

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Year:  2016        PMID: 27380124     DOI: 10.1097/BCR.0000000000000379

Source DB:  PubMed          Journal:  J Burn Care Res        ISSN: 1559-047X            Impact factor:   1.845


  3 in total

1.  Scald management protocols - outcome differences in two different time periods using different treatment strategies.

Authors:  M Elmasry; I Steinvall; J Thorfinn; A H Abbas; O A Adly; I Abdelrahman; M A Nagi; F Sjoberg
Journal:  Ann Burns Fire Disasters       Date:  2016-06-30

2.  Division of overall duration of stay into operative stay and postoperative stay improves the overall estimate as a measure of quality of outcome in burn care.

Authors:  Islam Abdelrahman; Moustafa Elmasry; Pia Olofsson; Ingrid Steinvall; Mats Fredrikson; Folke Sjoberg
Journal:  PLoS One       Date:  2017-03-31       Impact factor: 3.240

Review 3.  Porcine Xenograft and Epidermal Fully Synthetic Skin Substitutes in the Treatment of Partial-Thickness Burns: A Literature Review.

Authors:  Herbert L Haller; Sigrid E Blome-Eberwein; Ludwik K Branski; Joshua S Carson; Roselle E Crombie; William L Hickerson; Lars Peter Kamolz; Booker T King; Sebastian P Nischwitz; Daniel Popp; Jeffrey W Shupp; Steven E Wolf
Journal:  Medicina (Kaunas)       Date:  2021-04-30       Impact factor: 2.430

  3 in total

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