Literature DB >> 27379848

A new synthesis of S-aryl uracils from aryl thiols and 6-amino uracils in the presence of NCS.

Gholamhossein Khalili1.   

Abstract

Sulfenylchloride intermediates generated from the reaction of aryl thiols with N-chlorosuccinimide were trapped by 6-amino uracil derivatives to yield 6-amino-5-(arylthio)-pyrimidine-2,4(1H,3H)-dione compounds at room temperature.

Entities:  

Keywords:  N-Chlorosuccinimide; Sulfenylchloride; Thiol; Uracil

Mesh:

Substances:

Year:  2016        PMID: 27379848     DOI: 10.1007/s11030-016-9685-8

Source DB:  PubMed          Journal:  Mol Divers        ISSN: 1381-1991            Impact factor:   2.943


  10 in total

Review 1.  Targeted gene repair facilitated by peptide nucleic acids (PNA).

Authors:  Peter E Nielsen
Journal:  Chembiochem       Date:  2010-10-18       Impact factor: 3.164

2.  Synthesis and antiviral properties of (E)-5-(2-bromovinyl)-2'-deoxycytidine-related compounds.

Authors:  A S Jones; J R Sayers; R T Walker; E De Clercq
Journal:  J Med Chem       Date:  1988-01       Impact factor: 7.446

3.  Anthracene based base-discriminating fluorescent oligonucleotide probes for SNPs typing: synthesis and photophysical properties.

Authors:  Yoshio Saito; Kaori Motegi; Subhendu Sekhar Bag; Isao Saito
Journal:  Bioorg Med Chem       Date:  2006-08-04       Impact factor: 3.641

Review 4.  Pyrimidine as constituent of natural biologically active compounds.

Authors:  Irene M Lagoja
Journal:  Chem Biodivers       Date:  2005-01       Impact factor: 2.408

Review 5.  Uracils as a cellular weapon against viruses and mechanisms of viral escape.

Authors:  Stéphane Priet; Joséphine Sire; Gilles Quérat
Journal:  Curr HIV Res       Date:  2006-01       Impact factor: 1.581

6.  New arylthioindoles: potent inhibitors of tubulin polymerization. 2. Structure-activity relationships and molecular modeling studies.

Authors:  Gabriella De Martino; Michael C Edler; Giuseppe La Regina; Antonio Coluccia; Maria Chiara Barbera; Denise Barrow; Robert I Nicholson; Gabriela Chiosis; Andrea Brancale; Ernest Hamel; Marino Artico; Romano Silvestri
Journal:  J Med Chem       Date:  2006-02-09       Impact factor: 7.446

7.  C5-Modified nucleosides exhibiting anticancer activity.

Authors:  Yoon-Suk Lee; Sun Min Park; Hwan Mook Kim; Song-Kyu Park; Kiho Lee; Chang Woo Lee; Byeang Hyean Kim
Journal:  Bioorg Med Chem Lett       Date:  2009-06-21       Impact factor: 2.823

8.  Synthesis of aryl thioethers through the N-chlorosuccinimide-promoted cross-coupling reaction of thiols with Grignard reagents.

Authors:  Jun-Hao Cheng; Chintakunta Ramesh; Hsin-Lun Kao; Yu-Jen Wang; Chien-Ching Chan; Chin-Fa Lee
Journal:  J Org Chem       Date:  2012-10-25       Impact factor: 4.354

9.  A general palladium-catalyzed coupling of aryl bromides/triflates and thiols.

Authors:  Takahiro Itoh; Toshiaki Mase
Journal:  Org Lett       Date:  2004-11-25       Impact factor: 6.005

10.  A highly efficient procedure for 3-sulfenylation of indole-2-carboxylates.

Authors:  Kevin M Schlosser; Alexei P Krasutsky; Harriet W Hamilton; Jessica E Reed; Karen Sexton
Journal:  Org Lett       Date:  2004-03-04       Impact factor: 6.005

  10 in total
  1 in total

1.  Small-molecule mimicry hunting strategy in the imperial cone snail, Conus imperialis.

Authors:  Joshua P Torres; Zhenjian Lin; Maren Watkins; Paula Flórez Salcedo; Robert P Baskin; Shireen Elhabian; Helena Safavi-Hemami; Dylan Taylor; Jortan Tun; Gisela P Concepcion; Noel Saguil; Angel A Yanagihara; Yixin Fang; Jeffrey R McArthur; Han-Shen Tae; Rocio K Finol-Urdaneta; B Duygu Özpolat; Baldomero M Olivera; Eric W Schmidt
Journal:  Sci Adv       Date:  2021-03-12       Impact factor: 14.136

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.