Literature DB >> 2737899

The polymerase chain reaction and its applications.

A Milbourne, S Nakamura, J M Nakamura.   

Abstract

The advent of recombinant DNA technology has brought us many new techniques for the detection of genetic defects. With these methods it has become possible to do prenatal screening of the DNA of fetuses and to detect genetic defects that would lead to congenital disease. The biggest problem facing researchers has been the limited sensitivity of the techniques of molecular biology especially in detecting small changes in the DNA.

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Year:  1989        PMID: 2737899

Source DB:  PubMed          Journal:  Hawaii Med J        ISSN: 0017-8594


  2 in total

1.  Immobilization of polynucleotides on magnetic particles. Factors influencing hybridization efficiency.

Authors:  P J Day; P S Flora; J E Fox; M R Walker
Journal:  Biochem J       Date:  1991-09-15       Impact factor: 3.857

Review 2.  Infection with the human T-lymphotropic virus type I. A review for clinicians.

Authors:  A C Dixon; P S Dixon; J M Nakamura
Journal:  West J Med       Date:  1989-12
  2 in total

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