Literature DB >> 2737681

Chromosomal assignment of the alcohol dehydrogenase cluster locus to human chromosome 4q21-23 by in situ hybridization.

M Tsukahara1, A Yoshida.   

Abstract

Human class I alcohol dehydrogenase (alcohol:NAD+ oxidoreductase, EC 1.1.1.1; ADH) is the major enzyme involved in ethanol oxidation. Three highly homologous genes govern the synthesis of three types of subunits which form several ADH isozymes. The locus for class I ADH loci was previously assigned to q21-25 of chromosome 4 by somatic cell hybridization techniques. Analysis of grain positions by in situ hybridization of chromosomes indicated that the ADH cluster locus is on 4q21-23, probably 4q22.

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Year:  1989        PMID： 2737681     DOI： 10.1016/0888-7543(89)90304-2

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  6 in total

Review 1.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 2.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

3.  Alcohol and aldehyde dehydrogenase genotypes and alcoholism in Chinese men.

Authors:  H R Thomasson; H J Edenberg; D W Crabb; X L Mai; R E Jerome; T K Li; S P Wang; Y T Lin; R B Lu; S J Yin
Journal:  Am J Hum Genet       Date:  1991-04       Impact factor: 11.025

4.  Joint multipoint linkage analysis of multivariate qualitative and quantitative traits. II. Alcoholism and event-related potentials.

Authors:  J T Williams; H Begleiter; B Porjesz; H J Edenberg; T Foroud; T Reich; A Goate; P Van Eerdewegh; L Almasy; J Blangero
Journal:  Am J Hum Genet       Date:  1999-10       Impact factor: 11.025

5.  Multiplication of the class I alcohol dehydrogenase locus in mammalian evolution.

Authors:  M Yasunami; C S Chen; A Yoshida
Journal:  Biochem Genet       Date:  1990-12       Impact factor: 1.890

6.  A second generation radiation hybrid map to aid the assembly of the bovine genome sequence.

Authors:  Oliver C Jann; Jan Aerts; Michelle Jones; Nicola Hastings; Andy Law; Stephanie McKay; Elisa Marques; Aparna Prasad; Jody Yu; Stephen S Moore; Sandrine Floriot; Marie-Françoise Mahé; André Eggen; Licia Silveri; Riccardo Negrini; Elisabetta Milanesi; Paolo Ajmone-Marsan; Alessio Valentini; Cinzia Marchitelli; Maria C Savarese; Michal Janitz; Ralf Herwig; Steffen Hennig; Chiara Gorni; Erin E Connor; Tad S Sonstegard; Timothy Smith; Cord Drögemüller; John L Williams
Journal:  BMC Genomics       Date:  2006-11-06       Impact factor: 3.969
  6 in total

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