BACKGROUND/AIMS: The Sangre Por Salud (Blood for Health; SPS) Biobank was created for the purpose of expanding precision medicine research to include underrepresented Latino patients. It is the result of a unique collaboration between Mayo Clinic and Mountain Park Health Center, a federally qualified community health center in Phoenix, Arizona. This report describes the rationale, development, implementation, and characteristics of the SPS Biobank. METHODS: Latino adults (ages 18-85 years) who were active patients within Mountain Park Health Center's internal medicine practice in Phoenix, Ariz., and had no history of diabetes were eligible. Participants provided a personal and family history of chronic disease, completed a sociodemographic, psychosocial, and behavioral questionnaire, underwent a comprehensive cardiometabolic risk assessment (anthropometrics, blood pressure and labs), and provided blood samples for banking. Laboratory results of cardiometabolic testing were returned to the participants and their providers through the electronic health record. RESULTS: During the first 2 years of recruitment into the SPS Biobank, 2,335 patients were approached and 1,432 (61.3%) consented to participate; 1,354 (94.5%) ultimately completed all requisite questionnaires and medical evaluations. The cohort is primarily Spanish-speaking (72.9%), female (73.3%), with a mean age of 41.3 ± 12.5 years. Most participants were born outside of the US (77.9%) and do not have health insurance (77.5%). The prevalence of overweight (35.5%) and obesity (45.0%) was high, as was previously unidentified prediabetes (55.9%), type 2 diabetes (7.4%), prehypertension (46.8%), and hypertension (16.2%). The majority of participants rated their health as good to excellent (72.1%) and, as a whole, described their overall quality of life as high (7.9/10). CONCLUSION: Collaborative efforts such as the SPS Biobank are critical for ensuring that underrepresented minority populations are included in precision medicine initiatives and biomedical research that seeks to improve human health and reduce the burdens of disease.
BACKGROUND/AIMS: The Sangre Por Salud (Blood for Health; SPS) Biobank was created for the purpose of expanding precision medicine research to include underrepresented Latino patients. It is the result of a unique collaboration between Mayo Clinic and Mountain Park Health Center, a federally qualified community health center in Phoenix, Arizona. This report describes the rationale, development, implementation, and characteristics of the SPS Biobank. METHODS: Latino adults (ages 18-85 years) who were active patients within Mountain Park Health Center's internal medicine practice in Phoenix, Ariz., and had no history of diabetes were eligible. Participants provided a personal and family history of chronic disease, completed a sociodemographic, psychosocial, and behavioral questionnaire, underwent a comprehensive cardiometabolic risk assessment (anthropometrics, blood pressure and labs), and provided blood samples for banking. Laboratory results of cardiometabolic testing were returned to the participants and their providers through the electronic health record. RESULTS: During the first 2 years of recruitment into the SPS Biobank, 2,335 patients were approached and 1,432 (61.3%) consented to participate; 1,354 (94.5%) ultimately completed all requisite questionnaires and medical evaluations. The cohort is primarily Spanish-speaking (72.9%), female (73.3%), with a mean age of 41.3 ± 12.5 years. Most participants were born outside of the US (77.9%) and do not have health insurance (77.5%). The prevalence of overweight (35.5%) and obesity (45.0%) was high, as was previously unidentified prediabetes (55.9%), type 2 diabetes (7.4%), prehypertension (46.8%), and hypertension (16.2%). The majority of participants rated their health as good to excellent (72.1%) and, as a whole, described their overall quality of life as high (7.9/10). CONCLUSION: Collaborative efforts such as the SPS Biobank are critical for ensuring that underrepresented minority populations are included in precision medicine initiatives and biomedical research that seeks to improve human health and reduce the burdens of disease.
Authors: A Coates; C F Dillenbeck; D R McNeil; S B Kaye; K Sims; R M Fox; R L Woods; G W Milton; J Solomon; M H Tattersall Journal: Eur J Cancer Clin Oncol Date: 1983-11
Authors: M Fernanda Lima-Costa; James Macinko; Juliana Vaz de Melo Mambrini; Cibele C Cesar; Sérgio V Peixoto; Wagner C S Magalhães; Bernardo L Horta; Mauricio Barreto; Erico Castro-Costa; Josélia O A Firmo; Fernando A Proietti; Thiago Peixoto Leal; Maira R Rodrigues; Alexandre Pereira; Eduardo Tarazona-Santos Journal: PLoS One Date: 2015-12-17 Impact factor: 3.240
Authors: Gabriel Q Shaibi; Iftikhar J Kullo; Davinder P Singh; Richard R Sharp; Eleanna De Filippis; Idali Cuellar; Valentina Hernandez; Sharon Levey; Carmen Radecki Breitkopf; Janet E Olson; James R Cerhan; Lawrence J Mandarino; Stephen N Thibodeau; Noralane M Lindor Journal: Public Health Genomics Date: 2018-12-06 Impact factor: 2.000
Authors: Oscar D Parra; Lindsay N Kohler; Lori Landes; Alexis A Soto; Diana Garcia; Jacqueline Mullins; Patty Molina; Eladio Pereira; Douglas J Spegman; Lisa Soltani; Lawrence J Mandarino Journal: BMJ Open Diabetes Res Care Date: 2022-05
Authors: Janet E Olson; Euijung Ryu; Matthew A Hathcock; Ruchi Gupta; Joshua T Bublitz; Paul Y Takahashi; Suzette J Bielinski; Jennifer L St Sauver; Karen Meagher; Richard R Sharp; Stephen N Thibodeau; Mine Cicek; James R Cerhan Journal: BMJ Open Date: 2019-11-06 Impact factor: 2.692
Authors: Tarika Srinivasan; Erica J Sutton; Annika T Beck; Idali Cuellar; Valentina Hernandez; Joel E Pacyna; Gabriel Q Shaibi; Iftikhar J Kullo; Noralane M Lindor; Davinder Singh; Richard R Sharp Journal: J Prim Care Community Health Date: 2021 Jan-Dec
Authors: Dawn K Coletta; Leslea J Hlusko; G Richard Scott; Luis A Garcia; Celine M Vachon; Aaron D Norman; Janet L Funk; Gabriel Q Shaibi; Valentina Hernandez; Eleanna De Filippis; Lawrence J Mandarino Journal: PLoS One Date: 2021-10-07 Impact factor: 3.240
Authors: Matthew A Hathcock; Christine Kirt; Euijung Ryu; Josh Bublitz; Ruchi Gupta; Liwei Wang; Stephen N Thibodeau; Nicole L Larson; Mine S Cicek; James R Cerhan; Janet E Olson Journal: Front Public Health Date: 2020-02-04
Authors: Joel E Pacyna; Gabriel Q Shaibi; Alex Lee; Jamie O Byrne; Idali Cuellar; Erica J Sutton; Valentina Hernandez; Noralane M Lindor; Davinder Singh; Iftikhar J Kullo; Richard R Sharp Journal: Genet Med Date: 2021-01-26 Impact factor: 8.822