Literature DB >> 27373757

RETRACTED: Evaluation of behavioral problems after prenatal dexamethasone treatment in Swedish adolescents at risk of CAH.

Lena Wallensteen1, Marius Zimmermann1, Malin Thomsen Sandberg1, Anton Gezelius1, Anna Nordenström1, Tatja Hirvikoski2, Svetlana Lajic3.   

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the authors due to technical errors that have called into question the reliability of the data used to inform the author's conclusions. All data on cognitive and behavioral outcomes in CAH and non–CAH cases, treated or not treated with DEX prenatally, were put into a single Excel database. The authors had in total four different patient groups for each age group (5–6 y, 7–17 y and 18-35 y). The database consisted of 237 cases in total and there were multiple columns for the different outcome measures. When the behavioral data for the sub-cohort described in this paper (first trimester treated non-CAH cases and healthy population controls, age 7–17 y) were copied to another sheet and compressed/modified in preparation for statistical analysis in SPSS, an error occurred. This technological issue caused rows to shift and the data from the different groups got mixed up. In particular, the non–CAH group versus the control group were "contaminated" with cases from the wrong patient group. The authors discovered this mistake when they started to analyse the data from the other sub–groups of patients, the CAH cases and the adult cohort, which was after their original results had already been published in Hormones and Behavior in this manuscript "Evaluation of behavioral problems after prenatal dexamethasone treatment in Swedish adolescents at risk of CAH". It then became apparent that the entire data set was unreliable and needed to be re–analysed which is what has motivated the retraction of this article. The authors have recently completed this re–analysis and the results have been published here: https://www.sciencedirect.com/science/article/pii/S0018506X17300752
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Congenital adrenal hyperplasia; Dexamethasone; Prenatal treatment; Social functioning

Mesh:

Substances:

Year:  2016        PMID: 27373757     DOI: 10.1016/j.yhbeh.2016.06.011

Source DB:  PubMed          Journal:  Horm Behav        ISSN: 0018-506X            Impact factor:   3.587


  2 in total

Review 1.  Challenges in Prenatal Treatment with Dexamethasone.

Authors:  Bonnie McCann-Crosby; Frank Xavier Placencia; Oluyemisi Adeyemi-Fowode; Jennifer Dietrich; Rachel Franciskovich; Sheila Gunn; Marni Axelrad; Duong Tu; David Mann; Lefkothea Karaviti; Vernon Reid Sutton
Journal:  Pediatr Endocrinol Rev       Date:  2018-09

Review 2.  Caring for individuals with a difference of sex development (DSD): a Consensus Statement.

Authors:  Martine Cools; Anna Nordenström; Ralitsa Robeva; Joanne Hall; Puck Westerveld; Christa Flück; Birgit Köhler; Marta Berra; Alexander Springer; Katinka Schweizer; Vickie Pasterski
Journal:  Nat Rev Endocrinol       Date:  2018-07       Impact factor: 43.330

  2 in total

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