Literature DB >> 27373657

Hyrtinadines C and D, New Azepinoindole-Type Alkaloids from a Marine Sponge Hyrtios sp.

Takaaki Kubota1, Kenta Nakamura, Kanae Sakai, Jane Fromont, Tohru Gonoi, Jun'ichi Kobayashi.   

Abstract

New bisindole alkaloids, hyrtinadines C (1) and D (2), have been isolated from an Okinawan marine sponge Hyrtios sp. The structures of hyrtinadines C (1) and D (2) were elucidated based on analyses of the spectral data. Hyrtinadines C (1) and D (2) were the relatively rare alkaloids possessing a 3,4-fused azepinoindole skeleton. Hyrtinadines C (1) and D (2) showed antimicrobial activity.

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Year:  2016        PMID： 27373657     DOI： 10.1248/cpb.c16-00201

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  4 in total

Review 1.  Bioactive Natural Products of Marine Sponges from the Genus Hyrtios.

Authors:  Nourhan Hisham Shady; Ebaa M El-Hossary; Mostafa A Fouad; Tobias A M Gulder; Mohamed Salah Kamel; Usama Ramadan Abdelmohsen
Journal:  Molecules       Date:  2017-05-11       Impact factor: 4.411

2.  A Natural Quinazoline Derivative from Marine Sponge Hyrtios erectus Induces Apoptosis of Breast Cancer Cells via ROS Production and Intrinsic or Extrinsic Apoptosis Pathways.

Authors:  Arun Kumar De; Ramachandran Muthiyan; Samiran Mondal; Nilkamal Mahanta; Debasis Bhattacharya; Perumal Ponraj; Kangayan Muniswamy; Anandamoy Kundu; Madhu Sudhan Kundu; Jai Sunder; Dhanasekar Karunakaran; Asit Kumar Bera; Sibnarayan Dam Roy; Dhruba Malakar
Journal:  Mar Drugs       Date:  2019-11-23       Impact factor: 5.118

Review 3.  Marine Pharmacology in 2016-2017: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Antiprotozoal, Antituberculosis and Antiviral Activities; Affecting the Immune and Nervous Systems, and Other Miscellaneous Mechanisms of Action.

Authors:  Alejandro M S Mayer; Aimee J Guerrero; Abimael D Rodríguez; Orazio Taglialatela-Scafati; Fumiaki Nakamura; Nobuhiro Fusetani
Journal:  Mar Drugs       Date:  2021-01-21       Impact factor: 5.118

Review 4.  Marine Indole Alkaloids-Isolation, Structure and Bioactivities.

Authors:  Yong Hu; Siling Chen; Fang Yang; Shuai Dong
Journal:  Mar Drugs       Date:  2021-11-24       Impact factor: 5.118
  4 in total

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