PURPOSE: To report a case of acute posterior multifocal placoid pigment epitheliopathy (APMPPE), following influenza vaccination. CASE REPORT: An 18-year-old female patient developed a painless significant bilateral decrease of vision, moderate photophobia, metamorphopsia and intermittent headaches two weeks after having a seasonal anti-flu immunization. Clinical evaluation and ancillary testing pointed toward the diagnosis of APMPPE. The case evolved favorable after oral prednisone 0.5 mg/kg/day gradually decreased for over 4 weeks. A total recovery of visual function and no recurrences were noticed at 1, 3 and 5 years follow-up. CONCLUSIONS: Previous case reports already suggested a possible relationship between various immunizations and APMPPE onset. This case is the first one reported in our country. Epidemiological studies are required to link APMPPE occurrence and vaccination.
PURPOSE: To report a case of acute posterior multifocal placoid pigment epitheliopathy (APMPPE), following influenza vaccination. CASE REPORT: An 18-year-old female patient developed a painless significant bilateral decrease of vision, moderate photophobia, metamorphopsia and intermittent headaches two weeks after having a seasonal anti-flu immunization. Clinical evaluation and ancillary testing pointed toward the diagnosis of APMPPE. The case evolved favorable after oral prednisone 0.5 mg/kg/day gradually decreased for over 4 weeks. A total recovery of visual function and no recurrences were noticed at 1, 3 and 5 years follow-up. CONCLUSIONS: Previous case reports already suggested a possible relationship between various immunizations and APMPPE onset. This case is the first one reported in our country. Epidemiological studies are required to link APMPPE occurrence and vaccination.
Authors: Tito Fiore; Barbara Iaccheri; Sofia Androudi; Thekla G Papadaki; Fahd Anzaar; Periklis Brazitikos; Donald J D'Amico; C Stephen Foster Journal: Retina Date: 2009 Jul-Aug Impact factor: 4.256
Authors: Alexa L Li; Neal V Palejwala; Jessica G Shantha; Ghazala O'Keefe; Cecilia S Lee; Thomas Albini; Steven Yeh Journal: PLoS One Date: 2020-08-24 Impact factor: 3.752