Literature DB >> 2737264

Pyruvate kinase inhibited by L-cysteine as a marker of tumorigenic human urothelial cell lines.

M Gumińska1, M B Stachurska, B Christensen, V Tromholt, J Kieler, C Radzikowski, D Duś.   

Abstract

It was found that a decrease in electrophoretic mobility of pyruvate kinase (PK) isoenzyme, and an increase of the sensitivity of this enzyme to L-cysteine, were markers of immortalization and tumorigenic properties, respectively, in human urothelial cell lines characterized by different grades of transformation (TGr) in vitro.

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Year:  1989        PMID: 2737264     DOI: 10.1007/bf01990510

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  19 in total

1.  DISC ELECTROPHORESIS. II. METHOD AND APPLICATION TO HUMAN SERUM PROTEINS.

Authors:  B J DAVIS
Journal:  Ann N Y Acad Sci       Date:  1964-12-28       Impact factor: 5.691

2.  Metabolic control of glycolysis in normal and tumor permeabilized cells.

Authors:  M Gosalvez; S Garcia-Suarez; L Lopez-Alarcon
Journal:  Cancer Res       Date:  1978-01       Impact factor: 12.701

3.  In vitro studies of human bladder cancer.

Authors:  J Kieler; B Christensen; S Ottesen; V Tromholt; K Ostrowski
Journal:  Anticancer Res       Date:  1987 Sep-Oct       Impact factor: 2.480

4.  Established cell line of urinary bladder carcinoma (T24) containing tumour-specific antigen.

Authors:  J Bubeník; M Baresová; V Viklický; J Jakoubková; H Sainerová; J Donner
Journal:  Int J Cancer       Date:  1973-05       Impact factor: 7.396

5.  A new pyruvate kinase isozyme in hepatomas.

Authors:  W E Criss
Journal:  Biochem Biophys Res Commun       Date:  1969-06-27       Impact factor: 3.575

6.  Carbohydrate metabolism in cancer cells and the molecular correlation concept.

Authors:  G Weber
Journal:  Naturwissenschaften       Date:  1968-09

Review 7.  Enzymology of cancer cells (first of two parts).

Authors:  G Weber
Journal:  N Engl J Med       Date:  1977-03-03       Impact factor: 91.245

8.  Comparative studies of normal, 'spontaneously' transformed and malignant human urothelium cells in vitro.

Authors:  M Vilien; B Christensen; H Wolf; F Rasmussen; C Hou-Jensen; C O Povlsen
Journal:  Eur J Cancer Clin Oncol       Date:  1983-06

Review 9.  Invasiveness of transformed bladder epithelial cells.

Authors:  J F Kieler
Journal:  Cancer Metastasis Rev       Date:  1984       Impact factor: 9.264

10.  The inhibitory effect of L-cysteine and its derivatives on glycolysis in Ehrlich ascites tumour cells.

Authors:  T Kedryna; M Gumińska; E Marchut
Journal:  Biochim Biophys Acta       Date:  1983-08-17
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  1 in total

Review 1.  A critical review of the role of M2PYK in the Warburg effect.

Authors:  Robert A Harris; Aron W Fenton
Journal:  Biochim Biophys Acta Rev Cancer       Date:  2019-01-29       Impact factor: 10.680

  1 in total

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