Literature DB >> 27371521

Novel Biological Therapies Targeting Heart Failure: Myocardial Rejuvenation.

Amanda J Favreau-Lessard1, Sergey Ryzhov1, Douglas B Sawyer2.   

Abstract

Recovery of ventricular function occurs in a subset of patients with advanced heart failure treated with medical and/or mechanical therapy. Finding strategies that induce ventricular recovery through induction of repair, regeneration, or "rejuvenation" is a long-sought goal of research programs. Cell-based strategies, use of recombinant growth and survival factors, and gene delivery are under investigation. In this brief article we highlight a few of the biological approaches in development to treat heart failure.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Cell therapy; Gene therapy; Heart failure; Rejuvenation

Mesh：

Year:  2016        PMID： 27371521      PMCID： PMC5214584          DOI： 10.1016/j.hfc.2016.03.008

Source DB:  PubMed          Journal:  Heart Fail Clin        ISSN： 1551-7136            Impact factor:   3.179


  81 in total

1.  Cardiac Repair after Myocardial Infarction.

Authors:  Eva van Rooij
Journal:  N Engl J Med       Date:  2016-01-07       Impact factor: 91.245

2.  Effect of nesiritide in patients with acute decompensated heart failure.

Authors:  C M O'Connor; R C Starling; A F Hernandez; P W Armstrong; K Dickstein; V Hasselblad; G M Heizer; M Komajda; B M Massie; J J V McMurray; M S Nieminen; C J Reist; J L Rouleau; K Swedberg; K F Adams; S D Anker; D Atar; A Battler; R Botero; N R Bohidar; J Butler; N Clausell; R Corbalán; M R Costanzo; U Dahlstrom; L I Deckelbaum; R Diaz; M E Dunlap; J A Ezekowitz; D Feldman; G M Felker; G C Fonarow; D Gennevois; S S Gottlieb; J A Hill; J E Hollander; J G Howlett; M P Hudson; R D Kociol; H Krum; A Laucevicius; W C Levy; G F Méndez; M Metra; S Mittal; B-H Oh; N L Pereira; P Ponikowski; W H W Tang; W H Wilson; S Tanomsup; J R Teerlink; F Triposkiadis; R W Troughton; A A Voors; D J Whellan; F Zannad; R M Califf
Journal:  N Engl J Med       Date:  2011-07-07       Impact factor: 91.245

Review 3.  Harnessing the mesenchymal stem cell secretome for the treatment of cardiovascular disease.

Authors:  Sudhir H Ranganath; Oren Levy; Maneesha S Inamdar; Jeffrey M Karp
Journal:  Cell Stem Cell       Date:  2012-03-02       Impact factor: 24.633

4.  Mesenchymal Stem Cells as a Biological Drug for Heart Disease: Where Are We With Cardiac Cell-Based Therapy?

Authors:  Cristina Sanina; Joshua M Hare
Journal:  Circ Res       Date:  2015-07-17       Impact factor: 17.367

5.  Neuregulin-1 protects against doxorubicin-induced apoptosis in cardiomyocytes through an Akt-dependent pathway.

Authors:  T An; Y Zhang; Y Huang; R Zhang; S Yin; X Guo; Y Wang; C Zou; B Wei; R Lv; Q Zhou; J Zhang
Journal:  Physiol Res       Date:  2013-04-16       Impact factor: 1.881

Review 6.  Cardiac regeneration based on mechanisms of cardiomyocyte proliferation and differentiation.

Authors:  Samuel E Senyo; Richard T Lee; Bernhard Kühn
Journal:  Stem Cell Res       Date:  2014-09-28       Impact factor: 2.020

7.  In vitro evaluation of cenderitide-eluting stent I -an antirestenosis and proendothelization approach.

Authors:  Xu Wen Ng; Yingying Huang; Kerh Lin Liu; Soon Ghim Lim; Horng Haur Chen; John C Burnett; Yin Chiang Freddy Boey; Subbu S Venkatraman
Journal:  J Pharm Sci       Date:  2014-09-15       Impact factor: 3.534

8.  Intravenous glial growth factor 2 (GGF2) isoform of neuregulin-1β improves left ventricular function, gene and protein expression in rats after myocardial infarction.

Authors:  Michael F Hill; Amish V Patel; Abigail Murphy; Holly M Smith; Cristi L Galindo; Laura Pentassuglia; Xuyang Peng; Carrie G Lenneman; Oghenerukevwe Odiete; David B Friedman; Marvin W Kronenberg; Siyuen Zheng; Zhongming Zhao; Yanna Song; Frank E Harrell; Maya Srinivas; Anindita Ganguly; Jennifer Iaci; Tom J Parry; Anthony O Caggiano; Douglas B Sawyer
Journal:  PLoS One       Date:  2013-02-21       Impact factor: 3.240

9.  Anti-remodeling and anti-fibrotic effects of the neuregulin-1β glial growth factor 2 in a large animal model of heart failure.

Authors:  Cristi L Galindo; Ehab Kasasbeh; Abigail Murphy; Sergey Ryzhov; Sean Lenihan; Farhaan A Ahmad; Philip Williams; Amy Nunnally; Jamie Adcock; Yanna Song; Frank E Harrell; Truc-Linh Tran; Tom J Parry; Jen Iaci; Anindita Ganguly; Igor Feoktistov; Matthew K Stephenson; Anthony O Caggiano; Douglas B Sawyer; John H Cleator
Journal:  J Am Heart Assoc       Date:  2014-10-23       Impact factor: 5.501

10.  Calcium upregulation by percutaneous administration of gene therapy in patients with cardiac disease (CUPID 2): a randomised, multinational, double-blind, placebo-controlled, phase 2b trial.

Authors:  Barry Greenberg; Javed Butler; G Michael Felker; Piotr Ponikowski; Adriaan A Voors; Akshay S Desai; Denise Barnard; Alain Bouchard; Brian Jaski; Alexander R Lyon; Janice M Pogoda; Jeffrey J Rudy; Krisztina M Zsebo
Journal:  Lancet       Date:  2016-01-21       Impact factor: 79.321
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  3 in total

1.  Effects of endogenous serum neuregulin-1β on morbidity and mortality in patients with heart failure and left ventricular systolic dysfunction.

Authors:  Jennifer Miao; Shi Huang; Yan Ru Su; Carrie A Lenneman; Meera Wright; Frank E Harrell; Douglas B Sawyer; Daniel J Lenihan
Journal:  Biomarkers       Date:  2018-08-17       Impact factor: 2.658

Review 2.  Study of Natural Longlife Juvenility and Tissue Regeneration in Caudate Amphibians and Potential Application of Resulting Data in Biomedicine.

Authors:  Eleonora N Grigoryan
Journal:  J Dev Biol       Date:  2021-01-18

Review 3.  How to Stimulate Myocardial Regeneration in Adult Mammalian Heart: Existing Views and New Approaches.

Authors:  Galina Belostotskaya; Marc Hendrikx; Michael Galagudza; Sergey Suchkov
Journal:  Biomed Res Int       Date:  2020-03-03       Impact factor: 3.411
  3 in total

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