Literature DB >> 27370938

Neurochemical correlation between major depressive disorder and neurodegenerative diseases.

Gislaine Z Réus1, Stephanie E Titus2, Helena M Abelaira3, Sharon M Freitas3, Talita Tuon3, João Quevedo4, Josiane Budni3.   

Abstract

Major depressive disorder (MDD) is one of the most prevalent and life-threatening forms of mental illnesses affecting elderly people and has been associated with poor cognitive function. Recent evidence suggests a strong relationship between MDD and neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), Amyotrophic Lateral Sclerosis (ALS), as well as natural processes of aging. Changes in the neuroplasticity, morphology, and neurotransmission in the brain are seem to be associated to both, MDD and neurodegenerative diseases. In addition, there is evidence that psychological stress and MDD are associated with molecular and cellular signs of accelerated aging. This review will highlight the relationship between MDD, the aging process, and neurodegenerative diseases, emphasizing the neurochemical processes involved.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Aging; Alzheimer's disease; Amyotrophic Lateral Sclerosis; Huntington's disease; Major depressive disorder; Parkinson's disease

Mesh：

Year:  2016        PMID： 27370938     DOI： 10.1016/j.lfs.2016.06.027

Source DB:  PubMed          Journal:  Life Sci        ISSN： 0024-3205            Impact factor:   5.037


  5 in total

1.  Resveratrol, Endocrine Disrupting Chemicals, Neurodegenerative Diseases and Depression: Genes, Transcription Factors, microRNAs, and Sponges Involved.

Authors:  Hai Duc Nguyen
Journal:  Neurochem Res       Date:  2022-10-16       Impact factor: 4.414

2.  Psychiatric disorders prior to amyotrophic lateral sclerosis.

Authors:  Martin R Turner; Raph Goldacre; Kevin Talbot; Michael J Goldacre
Journal:  Ann Neurol       Date:  2016-11-14       Impact factor: 10.422

Review 3.  Targeting psychologic stress signaling pathways in Alzheimer's disease.

Authors:  Hunter S Futch; Cara L Croft; Van Q Truong; Eric G Krause; Todd E Golde
Journal:  Mol Neurodegener       Date:  2017-06-21       Impact factor: 14.195

4.  MicroRNA Profiling and Bioinformatics Target Analysis in Dorsal Hippocampus of Chronically Stressed Rats: Relevance to Depression Pathophysiology.

Authors:  Mauricio Muñoz-Llanos; María A García-Pérez; Xiaojiang Xu; Macarena Tejos-Bravo; Elena A Vidal; Tomás C Moyano; Rodrigo A Gutiérrez; Felipe I Aguayo; Aníbal Pacheco; Gonzalo García-Rojo; Esteban Aliaga; Paulina S Rojas; John A Cidlowski; Jenny L Fiedler
Journal:  Front Mol Neurosci       Date:  2018-08-06       Impact factor: 5.639

5.  The neuroanatomy of social trust predicts depression vulnerability.

Authors:  Alan S R Fermin; Toko Kiyonari; Yoshie Matsumoto; Haruto Takagishi; Yang Li; Ryota Kanai; Masamichi Sakagami; Rei Akaishi; Naho Ichikawa; Masahiro Takamura; Satoshi Yokoyama; Maro G Machizawa; Hui-Ling Chan; Ayumu Matani; Shigeto Yamawaki; Go Okada; Yasumasa Okamoto; Toshio Yamagishi
Journal:  Sci Rep       Date:  2022-10-06       Impact factor: 4.996
  5 in total

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