| Literature DB >> 27370684 |
Lay-Kim Tan1, Baharin Mohd-Farid2, Sulaiman Salsabil2, Hussein Heselynn3, Sulaiman Wahinuddin4, Ing-Soo Lau5, Suk-Chyn Gun6, Sharil Nor-Suhaila3, M Eashwary3, Mohamed Said Mohd-Shahrir7, Mohd-Mokhtar Ainon8, Rosman Azmillah5, Othman Muhaini9, Murad Shahnaz2, Chun-Lai Too10.
Abstract
A total of 951 Southeast Asia Malays from Peninsular Malaysia were genotyped for HLA-A, -B, -C -DRB1, and -DQB1 loci using polymerase chain reaction sequence-specific oligonucleotide probe hybridization methods. In this report, there were significant deviation from Hardy-Weinberg proportions for the HLA-A (p<0.0001), -B (p<0.0001), -DRB1 (p<0.0001) and -DQB1 (p<0.01) loci. Minor deviations from HWEP were detected for HLA-C (p=0.01). This genotype data was available in Allele Frequencies Network Database (AFND) Gonzalez-Galarza et al. (2015).Entities:
Keywords: Genetic; HLA alleles; Malays; Population
Mesh:
Substances:
Year: 2016 PMID: 27370684 DOI: 10.1016/j.humimm.2016.06.022
Source DB: PubMed Journal: Hum Immunol ISSN: 0198-8859 Impact factor: 2.850