Literature DB >> 27370648

Quality of care provided to prostate cancer (PC) patients for prevention and treatment of osteoporosis induced by androgen deprivation therapy (ADT).

Rehab Chahin1, Husayn Gulamhusein1, Henriette Breunis1, Shabbir M H Alibhai2,3,4,5.   

Abstract

OBJECTIVES: This study aims to evaluate the quality of care (QOC) and use of validated risk algorithms provided in a specialized osteoporosis clinic to men with prostate cancer on androgen deprivation therapy (ADT) who are at risk of bone loss and fragility fractures. PATIENTS AND METHODS: Charts for 100 consecutive men (mean age 73.0 years) on ADT referred to a tertiary osteoporosis clinic in Toronto, Canada between 2010 and 2014 were reviewed. The following QOC issues were examined: (a) bone health services provided, i.e., screening, preventing, and treating osteoporosis; and (b) use of national guidelines and fracture risk assessment tools for targeting appropriate therapy.
RESULTS: The median (IQR) duration of ADT was 21.4 (26.9) months at the baseline visit. Nineteen patients had their first bone mineral density test before starting ADT and 34 during the first year of use. At initial consultation, 83 and 30 patients were taking inadequate amounts of calcium and vitamin D, respectively. A validated fracture risk assessment tool was used in all patients; 42 had a moderate 10-year fracture risk and 12 were high risk. Sixteen (72.7 %) of sedentary patients were advised to increase physical activity. Sixty-four (77.1 %) and 28 (93.3 %) of patients not taking appropriate amounts of calcium and vitamin D, respectively, were recommended to adjust their intake to guideline levels. All patients at high fracture risk were recommended a bisphosphonate.
CONCLUSIONS: The majority of referred patients had moderate to high fracture risk. The osteoporosis clinic recommended guideline-based bone health care for the vast majority of men on ADT.

Entities:  

Keywords:  Androgen deprivation therapy; Bone health; Prostate cancer; Quality of care

Mesh:

Substances:

Year:  2016        PMID: 27370648     DOI: 10.1007/s00520-016-3320-1

Source DB:  PubMed          Journal:  Support Care Cancer        ISSN: 0941-4355            Impact factor:   3.603


  43 in total

1.  2010 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada: summary.

Authors:  Alexandra Papaioannou; Suzanne Morin; Angela M Cheung; Stephanie Atkinson; Jacques P Brown; Sidney Feldman; David A Hanley; Anthony Hodsman; Sophie A Jamal; Stephanie M Kaiser; Brent Kvern; Kerry Siminoski; William D Leslie
Journal:  CMAJ       Date:  2010-10-12       Impact factor: 8.262

2.  Cost-effectiveness of fracture prevention in men who receive androgen deprivation therapy for localized prostate cancer.

Authors:  Kouta Ito; Elena B Elkin; Monica Girotra; Michael J Morris
Journal:  Ann Intern Med       Date:  2010-05-18       Impact factor: 25.391

3.  Bisphosphonate prescriptions in men with androgen deprivation therapy use.

Authors:  Husayn Gulamhusein; Lingsong Yun; Angela M Cheung; Rinku Sutradhar; Lawrence Paszat; Padraig Warde; Shabbir M H Alibhai
Journal:  JAMA       Date:  2014-12-03       Impact factor: 56.272

4.  Low rate of bone density testing in men receiving androgen deprivation therapy.

Authors:  Mary Kay Barton
Journal:  CA Cancer J Clin       Date:  2013-01-14       Impact factor: 508.702

5.  Bone health management in prostate cancer patients receiving androgen deprivation therapy.

Authors:  Vishnuprabha Dhanapal; David J Reeves
Journal:  J Oncol Pharm Pract       Date:  2011-08-01       Impact factor: 1.809

6.  Validation of a calcium assessment tool in postmenopausal Canadian women.

Authors:  Ada Hung; Maryam Hamidi; Ekaterina Riazantseva; Lilian Thompson; Lianne Tile; George Tomlinson; Brooke Stewart; Angela M Cheung
Journal:  Maturitas       Date:  2011-03-29       Impact factor: 4.342

7.  Prevalence of osteoporosis during long-term androgen deprivation therapy in patients with prostate cancer.

Authors:  Juan Morote; Jacques Planas Morin; Anna Orsola; Jose M Abascal; Carles Salvador; Enrique Trilla; Carles X Raventos; Lluis Cecchini; Gloria Encabo; Jaume Reventos
Journal:  Urology       Date:  2007-03       Impact factor: 2.649

Review 8.  Survivorship: adult cancer survivors.

Authors:  Patricia A Ganz
Journal:  Prim Care       Date:  2009-12       Impact factor: 2.907

9.  Guidelines adherence and hypertension control at a tertiary hospital in Malaysia.

Authors:  Nafees Ahmad; Yahaya Hassan; Balamurugan Tangiisuran; Ong Loke Meng; Noorizan Abd Aziz; Fiaz-ud-Din Ahmad; Muhammad Atif
Journal:  J Eval Clin Pract       Date:  2012-05-15       Impact factor: 2.431

10.  Management of decreased bone mineral density in men starting androgen-deprivation therapy for prostate cancer.

Authors:  Abbas H Panju; Henriette Breunis; Angela M Cheung; Marc Leach; Neil Fleshner; Padraig Warde; Sarah Duff-Canning; Murray Krahn; Gary Naglie; Ian Tannock; George Tomlinson; Shabbir M H Alibhai
Journal:  BJU Int       Date:  2008-10-24       Impact factor: 5.588

View more
  1 in total

1.  Healthy Bones Study: can a prescription coupled with education improve bone health for patients receiving androgen deprivation therapy?-a before/after study.

Authors:  Derek S Tsang; Jennifer M Jones; Osai Samadi; Suhayb Shah; Nicholas Mitsakakis; Charles N Catton; William Jeon; Joshua To; Henriette Breunis; Shabbir M H Alibhai
Journal:  Support Care Cancer       Date:  2018-03-12       Impact factor: 3.603

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.