Literature DB >> 27366760

Zika virus outbreak: an overview of the experimental therapeutics and treatment.

Shailendra K Saxena1, Asif Elahi1, Srinivasulu Gadugu1, Anil K Prasad1.   

Abstract

Zika virus (ZIKV) infection is a new emerging threat around the globe which might be responsible for microcephaly and Guillain-Barre syndrome in the infants. Recently, ZIKV outbreak has caused a public health crisis in Brazil after being linked to a sharp increase in birth defects. ZIKV is ssRNA virus belongs to the family Flaviviridae. It is mainly transmitted by mosquito bite specifically Aedes species and disease symptoms include fever, joint pain, muscle pain, rash, conjunctivitis, and headache. The reservoir of ZIKV is still not known. Protection at personal level by avoiding mosquito bite would help to reduce the incidence of the disease. Control of ZIKV infection by vaccination or antiviral drug either from modern, complementary and alternative medicines may be considered to be one of the most effective strategies in the long run. Large scale immunization of susceptible human population is highly required to prevent this deadly disease. Attempts should be made as soon as possible to develop effective vaccines or antiviral to prevent ZIKV infection. This article provides a current overview of the experimental therapeutics and treatment options based on modern, complementary and alternative medicines.

Entities:  

Keywords:  Aedes species; Infectious disease; Microcephaly; Risk assessment and prevention; Treatment; Zika virus

Year:  2016        PMID: 27366760      PMCID: PMC4909003          DOI: 10.1007/s13337-016-0307-y

Source DB:  PubMed          Journal:  Virusdisease        ISSN: 2347-3584


  17 in total

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Journal:  Trans R Soc Trop Med Hyg       Date:  1964-07       Impact factor: 2.184

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Journal:  Trans R Soc Trop Med Hyg       Date:  1958-05       Impact factor: 2.184

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Authors:  G W A DICK; S F KITCHEN; A J HADDOW
Journal:  Trans R Soc Trop Med Hyg       Date:  1952-09       Impact factor: 2.184

5.  Zika virus. II. Pathogenicity and physical properties.

Authors:  G W A DICK
Journal:  Trans R Soc Trop Med Hyg       Date:  1952-09       Impact factor: 2.184

Review 6.  Dengue virus life cycle: viral and host factors modulating infectivity.

Authors:  Izabela A Rodenhuis-Zybert; Jan Wilschut; Jolanda M Smit
Journal:  Cell Mol Life Sci       Date:  2010-04-06       Impact factor: 9.261

7.  Arthropod-borne viral infections of man in Nigeria, 1964-1970.

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Journal:  Ann Trop Med Parasitol       Date:  1975-03

8.  TWELVE ISOLATIONS OF ZIKA VIRUS FROM AEDES (STEGOMYIA) AFRICANUS (THEOBALD) TAKEN IN AND ABOVE A UGANDA FOREST.

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Journal:  Bull World Health Organ       Date:  1964       Impact factor: 9.408

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Authors:  J G Olson; T G Ksiazek
Journal:  Trans R Soc Trop Med Hyg       Date:  1981       Impact factor: 2.184

10.  Glycosylation of the dengue 2 virus E protein at N67 is critical for virus growth in vitro but not for growth in intrathoracically inoculated Aedes aegypti mosquitoes.

Authors:  Juliet E Bryant; Amanda E Calvert; Kyeen Mesesan; Mary B Crabtree; Katharine E Volpe; Shawn Silengo; Richard M Kinney; Claire Y-H Huang; Barry R Miller; John T Roehrig
Journal:  Virology       Date:  2007-06-01       Impact factor: 3.616

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  9 in total

Review 1.  Mosquito vectors and the spread of cancer: an overlooked connection?

Authors:  Giovanni Benelli; Annalisa Lo Iacono; Angelo Canale; Heinz Mehlhorn
Journal:  Parasitol Res       Date:  2016-04-07       Impact factor: 2.289

2.  A study on medical Internet of Things and Big Data in personalized healthcare system.

Authors:  V Jagadeeswari; V Subramaniyaswamy; R Logesh; V Vijayakumar
Journal:  Health Inf Sci Syst       Date:  2018-09-20

Review 3.  Electrochemical Biosensors for Early Stage Zika Diagnostics.

Authors:  Ajeet Kaushik; Sneham Tiwari; Rahul D Jayant; Arti Vashist; Roozbeh Nikkhah-Moshaie; Nazira El-Hage; Madhavan Nair
Journal:  Trends Biotechnol       Date:  2016-10-26       Impact factor: 19.536

Review 4.  Phytomedicines explored under in vitro and in silico studies against coronavirus: An opportunity to develop traditional medicines.

Authors:  Yashika Gandhi; Sujeet K Mishra; Hemant Rawat; Jyotika Grewal; Ravi Kumar; Santosh K Shakya; Vipin Kumar Jain; G Babu; Arjun Singh; Ravindra Singh; Rabinarayan Acharya; Vijay Kumar
Journal:  S Afr J Bot       Date:  2022-05-02       Impact factor: 3.111

5.  Motion-Based Immunological Detection of Zika Virus Using Pt-Nanomotors and a Cellphone.

Authors:  Mohamed Shehata Draz; Nivethitha Kota Lakshminaraasimulu; Sanchana Krishnakumar; Dheerendranath Battalapalli; Anish Vasan; Manoj Kumar Kanakasabapathy; Aparna Sreeram; Shantanu Kallakuri; Prudhvi Thirumalaraju; Yudong Li; Stephane Hua; Xu G Yu; Daniel R Kuritzkes; Hadi Shafiee
Journal:  ACS Nano       Date:  2018-05-16       Impact factor: 15.881

6.  Research and development of Zika virus vaccines.

Authors:  Brian E Dawes; Claire A Smalley; Bethany L Tiner; David Wc Beasley; Gregg N Milligan; Lisa M Reece; Joachim Hombach; Alan Dt Barrett
Journal:  NPJ Vaccines       Date:  2016-07-28       Impact factor: 7.344

Review 7.  Advances in Developing Therapies to Combat Zika Virus: Current Knowledge and Future Perspectives.

Authors:  Ashok Munjal; Rekha Khandia; Kuldeep Dhama; Swati Sachan; Kumaragurubaran Karthik; Ruchi Tiwari; Yashpal S Malik; Deepak Kumar; Raj K Singh; Hafiz M N Iqbal; Sunil K Joshi
Journal:  Front Microbiol       Date:  2017-08-03       Impact factor: 5.640

8.  Serologic evidence of West Nile virus and Saint Louis encephalitis virus in horses from Southern Brazil.

Authors:  Matheus N Weber; Ana C S Mosena; Letícia F Baumbach; Mariana S da Silva; Raíssa Canova; Débora R L Dos Santos; Renata da F Budaszewski; Livia V de Oliveira; Michel M Soane; Natália B Saraiva; Fernanda T Bellucco; Bruno Amaral Mazurek; Gustavo N Diehl; Laura H V G Gil; Mauro R Borba; Luis G Corbellini; Cláudio W Canal
Journal:  Braz J Microbiol       Date:  2021-04-02       Impact factor: 2.476

Review 9.  A review on Zika virus outbreak, epidemiology, transmission and infection dynamics.

Authors:  Syeda Sidra Kazmi; Waqar Ali; Nousheen Bibi; Faisal Nouroz
Journal:  J Biol Res (Thessalon)       Date:  2020-03-04       Impact factor: 1.889

  9 in total

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