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Literature DB >> 27366403

Factors Affecting Tissue Oxygenation in Erythrocyte Transfusions.

Abstract

Red blood cell transfusions are used to increase the oxygen-carrying capacity of blood in anemic states. But, because of the changes during storage of blood components and the specifics of preparation, erythrocytes may have controversial effects on tissue oxygenation and microcirculation. Also, the patient situation may play a role in the differing responses in oxygenation and microcirculation. In this review, the studies concerning the effects of banked blood and patient characteristics on microcirculation and tissue oxygenation are summarized.

Entities: Chemical Species

Keywords: Erythrocytes; blood transfusion; microcirculation

Year: 2014 PMID： 27366403 PMCID： PMC4894217 DOI： 10.5152/TJAR.2014.112014

Source DB: PubMed Journal: Turk J Anaesthesiol Reanim ISSN： 2149-276X

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References

47 in total

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Factors Affecting Tissue Oxygenation in Erythrocyte Transfusions.

1. Clinical outcomes following institution of the Canadian universal leukoreduction program for red blood cell transfusions.

Review 2. The endothelium: physiological functions and role in microcirculatory failure during severe sepsis.

3. Microvascular perfusion upon exchange transfusion with stored red blood cells in normovolemic anemic conditions.

4. Influence of antioxidants on the quality of stored blood.

5. Nitric oxide scavenging by red blood cell microparticles and cell-free hemoglobin as a mechanism for the red cell storage lesion.

6. Transfusion and postoperative pneumonia in coronary artery bypass graft surgery: effect of the length of storage of transfused red cells.

7. Age of transfused blood: an independent predictor of mortality despite universal leukoreduction.

8. S-nitrosohemoglobin deficiency: a mechanism for loss of physiological activity in banked blood.

9. Microvascular response to red blood cell transfusion in patients with severe sepsis.

Review 10. The microcirculation is the motor of sepsis.