Does Low Dose Lidocaine Cause Convulsions?

In anaesthesiology practice, lidocaine is commonly used for local and regional anaesthesia as well as to decrease haemodynamic response to intubation. Lidocain usage within the safe dose range is suggested and in case of overdose; systemic intoxication, central nervous system and cardiovascular system toxicity may occur. Convulsions, cardiac collapse and coma are reported in relation to overdoses of lidocain. In this report; the convulsion event, which occurred after injection of intravenous 1 mg kg(-1) 1% lidocaine to inhibit intubation-related hemodynamic side effects in patients scheduled for vitrectomy under general anaesthesia due to retinal detachment, is presented.