Literature DB >> 27366303

Treating chronic hepatitis B virus: Chinese physicians' awareness of the 2010 guidelines.

Lai Wei1, Ji-Dong Jia1, Xin-Hua Weng1, Xiao-Guang Dou1, Jia-Ji Jiang1, Hong Tang1, Qin Ning1, Qing-Qing Dai1, Run-Qin Li1, Jie Liu1.   

Abstract

AIM: To investigate Chinese physicians' awareness of the 2010 guidelines on the treatment of chronic hepatitis B virus (HBV) infection.
METHODS: This was a quantitative survey that investigated the characteristics and practices of physicians who were treating patients with hepatitis B, the profile of their patients and physician practices regarding the diagnosis and treatment of HBV at the time of the survey. Participants were randomly selected from available databases of Chinese physicians and requested to complete either an online or paper-based survey. Data from the survey responses were analysed. For data validation and interpretation, qualitative indepth interviews were conducted with 39 of the respondents.
RESULTS: Five-hundred completed surveys, from 663 physicians were available for analysis. A mean of 175 chronic hepatitis B (CHB) patients was seen by each physician every month, of whom 85 (49%) were treated in line with therapeutic indications stated in the 2010 guidelines. A total of 444 (89%) physicians often (> 60% of the time) adhered to the guidelines. Most physicians used antiviral medications as recommended. For patients with compensated and decompensated cirrhosis, 342 (68%) and 336 (67%) of physicians, respectively, often followed the recommendation to use potent nucleos(t)ide analogues with a high genetic barrier to resistance, using the appropriate treatment more than 60% of the time. Physicians from infectious disease or liver disease departments were better informed than those from gastrointestinal or other departments.
CONCLUSION: The majority of Chinese physicians often adhere to Chinese 2010 CHB guidelines and are well-informed about the use of antiviral medications for hepatitis B.

Entities:  

Keywords:  Awareness; China; Chronic hepatitis B; Physicians; Practice guidelines

Year:  2016        PMID: 27366303      PMCID: PMC4921798          DOI: 10.4254/wjh.v8.i18.762

Source DB:  PubMed          Journal:  World J Hepatol


  15 in total

Review 1.  Why don't physicians follow clinical practice guidelines? A framework for improvement.

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Journal:  JAMA       Date:  1999-10-20       Impact factor: 56.272

2.  Chronic hepatitis B: update 2009.

Authors:  Anna S F Lok; Brian J McMahon
Journal:  Hepatology       Date:  2009-09       Impact factor: 17.425

3.  Chronic hepatitis B virus infection and mortality from non-liver causes: results from the Haimen City cohort study.

Authors:  Gang Chen; Wenyao Lin; Fumin Shen; Uchenna H Iloeje; W Thomas London; Alison A Evans
Journal:  Int J Epidemiol       Date:  2005-01-19       Impact factor: 7.196

Review 4.  Epidemiology and prevention of hepatitis B virus infection in China.

Authors:  F M Lu; T Li; S Liu; H Zhuang
Journal:  J Viral Hepat       Date:  2010-03       Impact factor: 3.728

5.  Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2012 update.

Authors:  Yun-Fan Liaw; Jia-Horng Kao; Teerha Piratvisuth; Henry Lik Yuen Chan; Rong-Nan Chien; Chun-Jen Liu; Ed Gane; Stephen Locarnini; Seng-Gee Lim; Kwang-Hyub Han; Deepak Amarapurkar; Graham Cooksley; Wasim Jafri; Rosmawati Mohamed; Jin-Lin Hou; Wan-Long Chuang; Laurentius A Lesmana; Jose D Sollano; Dong-Jin Suh; Masao Omata
Journal:  Hepatol Int       Date:  2012-05-17       Impact factor: 6.047

6.  Hepatitis B and liver cancer knowledge and practices among healthcare and public health professionals in China: a cross-sectional study.

Authors:  Jonathan Chao; Ellen T Chang; Samuel K S So
Journal:  BMC Public Health       Date:  2010-02-25       Impact factor: 3.295

7.  Chronic hepatitis B: whom to treat and for how long? Propositions, challenges, and future directions.

Authors:  Sang Hoon Ahn; Henry L Y Chan; Pei-Jer Chen; Jun Cheng; Mahesh K Goenka; Jinlin Hou; Seng Gee Lim; Masao Omata; Teerha Piratvisuth; Qing Xie; Hyung Joon Yim; Man-Fung Yuen
Journal:  Hepatol Int       Date:  2010-02-20       Impact factor: 6.047

8.  A survey on the current trends in the management of hepatitis B in China.

Authors:  Lin-Hong Ning; Jia Hao; Zhong-Li Liao; Yuan-Yuan Zhou; Hong Guo; Xiao-Yan Zhao
Journal:  Eur J Gastroenterol Hepatol       Date:  2012-08       Impact factor: 2.566

9.  Epidemiological serosurvey of hepatitis B in China--declining HBV prevalence due to hepatitis B vaccination.

Authors:  Xiaofeng Liang; Shengli Bi; Weizhong Yang; Longde Wang; Gang Cui; Fuqiang Cui; Yong Zhang; Jianhua Liu; Xiaohong Gong; Yuansheng Chen; Fuzhen Wang; Hui Zheng; Feng Wang; Jing Guo; Zhiyuan Jia; Jingchen Ma; Huaqing Wang; Huiming Luo; Li Li; Shuigao Jin; Stephen C Hadler; Yu Wang
Journal:  Vaccine       Date:  2009-09-01       Impact factor: 3.641

10.  Do HIV care providers appropriately manage hepatitis B in coinfected patients treated with antiretroviral therapy?

Authors:  Mamta K Jain; Christopher K Opio; Chukwuma C Osuagwu; Rathi Pillai; Philip Keiser; William M Lee
Journal:  Clin Infect Dis       Date:  2007-02-21       Impact factor: 9.079

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