Literature DB >> 27365697

Profile of Live-born Infants of In-vitro Fertilisation.

S Narayan1, K S Rana2, M Sharma3, R K Sharma4, P Talwar5, K Kapur6, B K Goyal7.   

Abstract

INTRODUCTION: The Army Hospital (R&R) is the only service hospital providing in-vitro fertilisation (IVF) facility. Neonatal characteristics of live-born infants at this centre over a two-year period are analyzed in this study.
METHODS: Data on 504 consecutive live-born IVF infants over a two-year period (01 Feb 2007 to 31 Jan 2009) were analysed. RESULT: Of the 504 neonates, 190 (37.7%) were born by vaginal delivery, 156 (30.9%) by elective lower segment cesarean section (LSCS) and 127 (25.19%) following emergency LSCS. Maternal illness posing specific risk to the neonate was present in 165 out of 504 (32.7%). There were 239 (47.4%) preterm neonates. Males formed 51.8% of the cohort. Singletons accounted for 51.2%, while the rest (48.8%) were products of twin pregnancies. Small for gestational age neonates formed 22.6% (n = 114). A total of 20 (3.9%) infants had congenital malformations. There were 242 (48.1%) low birth weight neonates. A total of 128 (25.4%) neonates needed neonatal intensive care. Of the 504, there were 474 (94.1%) survivors while 30 (5.9%) did not survive. Twenty-nine (6.1%) neonates required readmission during the neonatal period.
CONCLUSION: In our setting, neonates born following IVF appeared to be at increased risk of prematurity, multiple births and low birth weight. Proper obstetric and neonatal management can result in good neonatal outcomes.

Entities:  

Keywords:  In-vitro fertilisation; Live-births; Low birth weight

Year:  2011        PMID: 27365697      PMCID: PMC4920915          DOI: 10.1016/S0377-1237(10)80085-1

Source DB:  PubMed          Journal:  Med J Armed Forces India        ISSN: 0377-1237


  16 in total

1.  Children conceived by in vitro fertilisation after fresh embryo transfer.

Authors:  S W D'Souza; E Rivlin; J Cadman; B Richards; P Buck; B A Lieberman
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  1997-03       Impact factor: 5.747

2.  World collaborative report on in vitro fertilization, 2000.

Authors:  G David Adamson; Jacques de Mouzon; Paul Lancaster; Karl-G Nygren; Elizabeth Sullivan; Fernando Zegers-Hochschild
Journal:  Fertil Steril       Date:  2006-06       Impact factor: 7.329

3.  Obstetric and neonatal outcome after single embryo transfer.

Authors:  P Poikkeus; M Gissler; L Unkila-Kallio; C Hyden-Granskog; A Tiitinen
Journal:  Hum Reprod       Date:  2007-01-24       Impact factor: 6.918

4.  Danish National In-Vitro Fertilization Registry 1994 and 1995: a controlled study of births, malformations and cytogenetic findings.

Authors:  H B Westergaard; A M Johansen; K Erb; A N Andersen
Journal:  Hum Reprod       Date:  1999-07       Impact factor: 6.918

Review 5.  Assisted reproductive technologies and the risk of birth defects--a systematic review.

Authors:  Michèle Hansen; Carol Bower; Elizabeth Milne; Nicholas de Klerk; Jennifer J Kurinczuk
Journal:  Hum Reprod       Date:  2004-11-26       Impact factor: 6.918

6.  Neurological sequelae in children born after in-vitro fertilisation: a population-based study.

Authors:  B Strömberg; G Dahlquist; A Ericson; O Finnström; M Köster; K Stjernqvist
Journal:  Lancet       Date:  2002-02-09       Impact factor: 79.321

7.  Assisted reproductive technology in the United States: 1998 results generated from the American Society for Reproductive Medicine/Society for Assisted Reproductive Technology Registry.

Authors: 
Journal:  Fertil Steril       Date:  2002-01       Impact factor: 7.329

8.  Perinatal outcome and congenital malformations in in-vitro fertilization babies from the Bourn-Hallam group.

Authors:  B Rizk; P Doyle; S L Tan; P Rainsbury; J Betts; P Brinsden; R Edwards
Journal:  Hum Reprod       Date:  1991-10       Impact factor: 6.918

9.  Growth, psychomotor development and morbidity up to 3 years of age in children born after IVF.

Authors:  S Koivurova; A-L Hartikainen; U Sovio; M Gissler; E Hemminki; M-R Järvelin
Journal:  Hum Reprod       Date:  2003-11       Impact factor: 6.918

10.  Congenital malformations in 4224 children conceived after IVF.

Authors:  S Anthony; S E Buitendijk; C A Dorrepaal; K Lindner; D D M Braat; A L den Ouden
Journal:  Hum Reprod       Date:  2002-08       Impact factor: 6.918

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