Literature DB >> 27365631

CURRENT STATUS OF DISULFIRAM THERAPY.

P K Chakraborty1, H Singh2, K J Divinakumar3.   

Abstract

The effectiveness of disulfiram is linked to the disulfiram-ethanol reaction in the treatment of Alcohol Dependence Syndrome. However disulfiram therapy is associated with various adverse effects and needs a structured and supervised after care program. Relapse rate is very high once disulfiram therapy is discontinued. Keeping these factors in mind disulfiram therapy is used less often today than previously.

Entities:  

Keywords:  Adverse drug reaction (ADR); Alcohol Dependence Syndrome (ADS); Disulfiram (Antabuse); Disulfiram-ethanol reaction (DER)

Year:  2011        PMID： 27365631      PMCID： PMC4924115          DOI： 10.1016/S0377-1237(01)80013-7

Source DB:  PubMed          Journal:  Med J Armed Forces India        ISSN： 0377-1237


  9 in total

1.  Long-term Antabuse treatment: tolerance and reasons for withdrawal.

Authors:  C Børup; A Kaiser; E Jensen
Journal:  Acta Psychiatr Scand Suppl       Date:  1992

Review 2.  Techniques to enhance compliance with disulfiram.

Authors:  J P Allen; R Z Litten
Journal:  Alcohol Clin Exp Res       Date:  1992-12       Impact factor: 3.455

3.  Psychosis during disulfiram therapy for alcoholism.

Authors:  K K Murthy
Journal:  J Indian Med Assoc       Date:  1997-03

Review 4.  Disulfiram treatment of patients with both alcohol dependence and other psychiatric disorders: a review.

Authors:  E W Larson; A Olincy; T A Rummans; R M Morse
Journal:  Alcohol Clin Exp Res       Date:  1992-02       Impact factor: 3.455

Review 5.  Safety issues concerning the use of disulfiram in treating alcohol dependence.

Authors:  J Chick
Journal:  Drug Saf       Date:  1999-05       Impact factor: 5.606

6.  Monitoring relapse drinking during disulfiram therapy by assay of urinary 5-hydroxytryptophol.

Authors:  A Helander
Journal:  Alcohol Clin Exp Res       Date:  1998-02       Impact factor: 3.455

7.  [Collateral effects of disulfiram on the central nervous system in alcoholics that have become totally abstemious. Description of 8 cases].

Authors:  S Maccari; W Giglioli; E Semrov; G Fornaciari
Journal:  Ann Ital Med Int       Date:  1996 Oct-Dec

Review 8.  [Disulfiram (Esperal) toxicity. Apropos of 3 original cases].

Authors:  O Dupuy; F Flocard; C Vial; G Rode; N Charles; D Boisson; A Flechaire
Journal:  Rev Med Interne       Date:  1995       Impact factor: 0.728

9.  Disulfiram therapy--adverse drug reactions and interactions.

Authors:  H Enghusen Poulsen; S Loft; J R Andersen; M Andersen
Journal:  Acta Psychiatr Scand Suppl       Date:  1992
  9 in total

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