| Literature DB >> 27365083 |
Marissa A H den Hoed1,2, Saskia M F Pluijm1,2, André G Uitterlinden3, Rob Pieters2, Marry M van den Heuvel-Eibrink4,5.
Abstract
Osteonecrosis is a disabling complication of treatment for pediatric acute lymphoblastic leukemia, and much effort has been made to predict which patients are prone to develop this disease. Multiple clinical and genetic factors have already been identified as being associated with osteonecrosis; however, a prediction model that combines pretreatment genetic biomarkers and clinical factors has not yet been designed. Such a prediction model can only be developed with continuing international collaborations and research efforts, including large genome-wide association studies.Entities:
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Year: 2016 PMID： 27365083 DOI： 10.1007/s40291-016-0226-z
Source DB: PubMed Journal: Mol Diagn Ther ISSN： 1177-1062 Impact factor: 4.074