Literature DB >> 27364782

Case of acute lead toxicity associated with Ayurvedic supplements.

Amelia Breyre1, Judith Green-McKenzie1.   

Abstract

Use of traditional folkloric remedies not disclosed to the physician may be difficult to identify as a source of lead toxicity. This report illustrates the presentation of a 26-year-old man who, during his 1 month vacation in India, was treated for low back pain with Ayurvedic herbal medicine. On his return to the USA, he presented to the emergency department with epigastric pain, weight loss, dark stools, nausea and vomiting. He was admitted and noted to be anaemic with a blood lead level (BLL) of 94.8 µg/dL. Peripheral blood smear demonstrated basophilic stippling. Chelation therapy with succimer was initiated. The patient became asymptomatic within months. Three years later, he remained asymptomatic with BLL <20 µg/dL. Physicians should be cognisant of potential toxicity from these Ayurvedic medications and have a heightened level of suspicion for lead toxicity in the face of anaemia and abdominal pain without obvious cause. 2016 BMJ Publishing Group Ltd.

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Year:  2016        PMID: 27364782      PMCID: PMC4932351          DOI: 10.1136/bcr-2016-215041

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  24 in total

1.  Lead poisoning associated with Ayurvedic drug presenting as intestinal obstruction: a case report.

Authors:  Nikhil Gupta; Binita Goswami; Nahar Singh; Ramesh Garg
Journal:  Clin Chim Acta       Date:  2010-10-13       Impact factor: 3.786

2.  Occult lead poisoning from Ayurvedic medicine produced, prescribed and purchased in India.

Authors:  Nilika G Wijeratne; James C G Doery; Andis Graudins
Journal:  Med J Aust       Date:  2011-02-21       Impact factor: 7.738

3.  Adult blood lead epidemiology and surveillance--United States, 2008-2009.

Authors: 
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4.  Measurement of the flux of lead from bone to blood in a nonhuman primate (Macaca fascicularis) by sequential administration of stable lead isotopes.

Authors:  M J Inskip; C A Franklin; C L Baccanale; W I Manton; E J O'Flaherty; C M Edwards; J B Blenkinsop; E B Edwards
Journal:  Fundam Appl Toxicol       Date:  1996-10

5.  Blood Lead Level (BLL) in the Adult Population of Jodhpur: A Pilot Study.

Authors:  Shailja Chambial; Kamla Kant Shukla; Shailendra Dwivedi; Pankaj Bhardwaj; Praveen Sharma
Journal:  Indian J Clin Biochem       Date:  2015-04-05

6.  Ayurvedic remedy for diabetes as a cause of lead poisoning: a case report.

Authors:  Amishi Desai; Harry Staszewski
Journal:  Am J Med       Date:  2012-07-13       Impact factor: 4.965

Review 7.  The use of chelating agents in occupational lead poisoning.

Authors:  S Porru; L Alessio
Journal:  Occup Med (Lond)       Date:  1996-02       Impact factor: 1.611

Review 8.  The interpretation of zinc protoporphyrin changes in lead intoxication: a case report and review of the literature.

Authors:  C J Martin; C L Werntz; A M Ducatman
Journal:  Occup Med (Lond)       Date:  2004-12       Impact factor: 1.611

Review 9.  Recommendations for medical management of adult lead exposure.

Authors:  Michael J Kosnett; Richard P Wedeen; Stephen J Rothenberg; Karen L Hipkins; Barbara L Materna; Brian S Schwartz; Howard Hu; Alan Woolf
Journal:  Environ Health Perspect       Date:  2006-12-22       Impact factor: 9.031

10.  Lead Poisoning and Anemia Associated with Use of Ayurvedic Medications Purchased on the Internet--Wisconsin, 2015.

Authors:  Jon Meiman; Robert Thiboldeaux; Henry Anderson
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2015-08-21       Impact factor: 17.586

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