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Literature DB >> 27358851

Isolated factor V deficiency in a patient with elevated PT and aPTT during routine pre-operative laboratory screening.

Keyur Thakar¹, Kaushal Parikh¹, Yamei Chen¹, Delong Liu¹.

Abstract

Isolated factor V (FV) deficiency is a rare disorder with approximately 150 cases reported in the literature since 1943. Bleeding symptoms from FV deficiency vary widely. FV deficiency usually manifests early in the life. We present a 59-year-old case with FV deficiency discovered during pre-operative laboratory screen.

Entities: Disease Species

Keywords: Factor V deficiency (FV deficiency); coagulopathy; hemostasis

Year: 2014 PMID： 27358851 PMCID： PMC4923507 DOI： 10.3978/j.issn.2306-9759.2014.03.02

Source DB: PubMed Journal: Stem Cell Investig ISSN： 2306-9759

17 in total

Review 1. Factor V: a combination of Dr Jekyll and Mr Hyde.

Authors: Kenneth G Mann; Michael Kalafatis
Journal: Blood Date: 2002-08-08 Impact factor: 22.113

2. Response of factor V inhibitor to rituximab in a patient who received liver transplantation for primary biliary cirrhosis.

Authors: Eric Chun-Yet Lian; Andreas G Tzakis; David Andrews
Journal: Am J Hematol Date: 2004-12 Impact factor: 10.047

3. Rare bleeding disorders.

Authors: Flora Peyvandi; Emmanuel J Favaloro
Journal: Semin Thromb Hemost Date: 2009-07-13 Impact factor: 4.180

4. The contribution of bovine Factor V and Factor Va to the activity of prothrombinase.

Authors: M E Nesheim; J B Taswell; K G Mann
Journal: J Biol Chem Date: 1979-11-10 Impact factor: 5.157

5. Residual platelet factor V ensures thrombin generation in patients with severe congenital factor V deficiency and mild bleeding symptoms.

Authors: Connie Duckers; Paolo Simioni; Luca Spiezia; Claudia Radu; Paolo Dabrilli; Sabrina Gavasso; Jan Rosing; Elisabetta Castoldi
Journal: Blood Date: 2009-10-27 Impact factor: 22.113

1. Successful coronary stenting in a patient with factor V deficiency in the absence of fresh frozen plasma transfusion: Case report.

Authors: Seongil Choi; MooKon Song
Journal: Medicine (Baltimore) Date: 2017-12 Impact factor: 1.817

2. Aortic Valve Replacement in Severe Factor V Deficiency and Inhibitor: Diagnostic and Management Challenges.

Authors: Alexa Bello; Eric Salazar; Kirk Heyne; Joseph Varon
Journal: Cureus Date: 2019-10-15

2 in total

Isolated factor V deficiency in a patient with elevated PT and aPTT during routine pre-operative laboratory screening.

Review 1. Factor V: a combination of Dr Jekyll and Mr Hyde.

2. Response of factor V inhibitor to rituximab in a patient who received liver transplantation for primary biliary cirrhosis.

3. Rare bleeding disorders.

4. The contribution of bovine Factor V and Factor Va to the activity of prothrombinase.

5. Residual platelet factor V ensures thrombin generation in patients with severe congenital factor V deficiency and mild bleeding symptoms.

6. The role of phospholipids and factor Va in the prothrombinase complex.

7. Rare Bleeding Disorder Registry: deficiencies of factors II, V, VII, X, XIII, fibrinogen and dysfibrinogenemias.

8. Factor 5 mutation profile in German patients with homozygous and heterozygous factor V deficiency.

9. High-dose intravenous immunoglobulin treatment in two patients with acquired factor V inhibitors.

10. Successful treatment with rituximab in a patient with an acquired factor V inhibitor.

1. Successful coronary stenting in a patient with factor V deficiency in the absence of fresh frozen plasma transfusion: Case report.

2. Aortic Valve Replacement in Severe Factor V Deficiency and Inhibitor: Diagnostic and Management Challenges.