Jarne M van Hattem1, Maris S Arcilla2, Martin Cj Bootsma3, Perry J van Genderen4, Abraham Goorhuis5, Martin P Grobusch5, Nicky Molhoek6, Astrid Ml Oude Lashof7, Constance Schultsz1, Ellen E Stobberingh7, Henri A Verbrugh2, Menno D de Jong1, Damian C Melles2, John Penders7. 1. Academic Medical Center, Department of Medical Microbiology, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. 2. Erasmus University Medical Center, Department of Medical Microbiology & Infectious Diseases, 's-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands. 3. Utrecht University, Department of Mathematics, Faculty of Science, Budapestlaan 6, 3584 CD Utrecht, The Netherlands. 4. Havenziekenhuis - Institute for Tropical Diseases, Department of Internal Medicine, Haringvliet 2, 3011 TD Rotterdam, The Netherlands. 5. Academic Medical Center, Center for Tropical Medicine & Travel Medicine, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. 6. Havenziekenhuis - Travel Clinic Harbour Hospital, Haringvliet 2, 3011 TD Rotterdam, The Netherlands. 7. Maastricht University Medical Center, NUTRIM School for Nutrition & Translational Research in Metabolism and Caphri School for Public Health & Primary Care, Department of Medical Microbiology, PO 5800, 6202 AZ Maastricht, The Netherlands.
Abstract
AIM: The aim was to study acquisition and persistence of carbapenemase-producing Enterobacteriaceae (CPE) among travelers. MATERIALS & METHODS: Stools from 2001 travelers and 215 nontraveling household members, collected before and immediately post-travel as well as 1, 3, 6 and 12 months upon return, were screened for CPE. RESULTS: Five travelers, all visiting Asia outside the Indian subcontinent, acquired CPE. One traveler persistently carried the same OXA-244 CPE up to 6 months post-travel. Three months after travel, her co-traveling spouse also became positive for this OXA-244 CPE strain, suggesting clonal transmission within this household. CONCLUSION: Acquisition of CPE is not restricted to travelers to the Indian subcontinent and/or to travelers seeking healthcare during travel and can persist up to at least 6 months post-travel.
AIM: The aim was to study acquisition and persistence of carbapenemase-producing Enterobacteriaceae (CPE) among travelers. MATERIALS & METHODS: Stools from 2001 travelers and 215 nontraveling household members, collected before and immediately post-travel as well as 1, 3, 6 and 12 months upon return, were screened for CPE. RESULTS: Five travelers, all visiting Asia outside the Indian subcontinent, acquired CPE. One traveler persistently carried the same OXA-244 CPE up to 6 months post-travel. Three months after travel, her co-traveling spouse also became positive for this OXA-244 CPE strain, suggesting clonal transmission within this household. CONCLUSION: Acquisition of CPE is not restricted to travelers to the Indian subcontinent and/or to travelers seeking healthcare during travel and can persist up to at least 6 months post-travel.
Authors: Alainna J Jamal; Amna Faheem; Lubna Farooqi; Xi Zoe Zhong; Irene Armstrong; David A Boyd; Emily Borgundvaag; Brenda L Coleman; Karen Green; Kithsiri Jayasinghe; Jennie Johnstone; Kevin Katz; Philipp Kohler; Angel X Li; Laura Mataseje; Roberto Melano; Matthew P Muller; Michael R Mulvey; Sarah Nayani; Samir N Patel; Aimee Paterson; Susan Poutanen; Anu Rebbapragada; David Richardson; Alicia Sarabia; Shumona Shafinaz; Andrew E Simor; Barbara M Willey; Laura Wisely; Allison J McGeer Journal: Clin Infect Dis Date: 2021-12-06 Impact factor: 9.079
Authors: Cliodna A M McNulty; Donna M Lecky; Li Xu-McCrae; Deborah Nakiboneka-Ssenabulya; Keun-Taik Chung; Tom Nichols; Helen Lucy Thomas; Mike Thomas; Adela Alvarez-Buylla; Kim Turner; Sahida Shabir; Susan Manzoor; Stephen Smith; Linda Crocker; Peter M Hawkey Journal: J Antimicrob Chemother Date: 2018-05-01 Impact factor: 5.790
Authors: Katrin Kremer; Rolf Kramer; Bernd Neumann; Sebastian Haller; Niels Pfennigwerth; Guido Werner; Sören Gatermann; Horst Schroten; Tim Eckmanns; Jörg B Hans Journal: Euro Surveill Date: 2020-06
Authors: Anne F Voor In 't Holt; Kees Mourik; Berend Beishuizen; Adriënne S van der Schoor; Annelies Verbon; Margreet C Vos; Juliëtte A Severin Journal: Antimicrob Resist Infect Control Date: 2020-05-20 Impact factor: 4.887
Authors: Alaric W D'Souza; Manish Boolchandani; Sanket Patel; Gianluca Galazzo; Jarne M van Hattem; Maris S Arcilla; Damian C Melles; Menno D de Jong; Constance Schultsz; Gautam Dantas; John Penders Journal: Genome Med Date: 2021-06-07 Impact factor: 11.117
Authors: A P Magiorakos; K Burns; J Rodríguez Baño; M Borg; G Daikos; U Dumpis; J C Lucet; M L Moro; E Tacconelli; G Skov Simonsen; E Szilágyi; A Voss; J T Weber Journal: Antimicrob Resist Infect Control Date: 2017-11-15 Impact factor: 4.887