| Literature DB >> 27357119 |
Yuan Tian1, Dongyuan Wang, Jingxu Li, Chuan Shi, Hui Zhao, Xiaogang Niu, Zigang Li.
Abstract
We report herein a proline-derived transannular N-cap as a helix nucleating template in diverse bio-related peptide sequences via macrolactamization on resin. This approach takes advantage of synergistic stabilization effects of both N-capping properties of proline and substitution of a main chain hydrogen bond with a covalent bond.Entities:
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Year: 2016 PMID： 27357119 DOI： 10.1039/c6cc04672j
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222