OBJECTIVE: To study the acute inhalation toxicity of 50% Luowei, a plant molluscacide, in rats. METHODS: Twenty adult Wistar rats, half male and half female, were given of 5000 mg/m³ of 50% Luowei through a dynamic inhalation device and the death and recovery of the rats were observed within 14 days, and LC₅₀ was drawn. RESULTS: After exposure, the activities of the rats decreased and a few individual animals had scratching symptom, but the symptom disappeared after the exposure. No animals died during the whole observation period. Therefore, the acute inhalation LC₅₀ was greater than 5000 mg/m³ for rats, and Luowei belonged to low toxicity level. CONCLUSIONS: 50% Luowei will not cause animal death if it is inhaled into animal body. However, people still need to wear protective equipment in production and use.
OBJECTIVE: To study the acute inhalation toxicity of 50% Luowei, a plant molluscacide, in rats. METHODS: Twenty adult Wistar rats, half male and half female, were given of 5000 mg/m³ of 50% Luowei through a dynamic inhalation device and the death and recovery of the rats were observed within 14 days, and LC₅₀ was drawn. RESULTS: After exposure, the activities of the rats decreased and a few individual animals had scratching symptom, but the symptom disappeared after the exposure. No animals died during the whole observation period. Therefore, the acute inhalation LC₅₀ was greater than 5000 mg/m³ for rats, and Luowei belonged to low toxicity level. CONCLUSIONS: 50% Luowei will not cause animal death if it is inhaled into animal body. However, people still need to wear protective equipment in production and use.