Literature DB >> 27356213

Fructokinase A acts as a protein kinase to promote nucleotide synthesis.

Xinjian Li1, Xu Qian1, Zhimin Lu1,2,3.   

Abstract

Keywords:  KHK; KHK-A; KHK-C; PGK1; PKM2; PRPS1; c-Myc; hepatocellular carcinoma; phosphorylation; tumorigenesis

Mesh：

Substances：

Year:  2016        PMID： 27356213      PMCID： PMC5053577          DOI： 10.1080/15384101.2016.1204861

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  7 in total

1.  Metabolic syndrome: F stands for fructose and fat.

Authors:  Costas A Lyssiotis; Lewis C Cantley
Journal:  Nature       Date:  2013-10-10       Impact factor: 49.962

2.  Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice.

Authors:  Takuji Ishimoto; Miguel A Lanaspa; Myphuong T Le; Gabriela E Garcia; Christine P Diggle; Paul S Maclean; Matthew R Jackman; Aruna Asipu; Carlos A Roncal-Jimenez; Tomoki Kosugi; Christopher J Rivard; Shoichi Maruyama; Bernardo Rodriguez-Iturbe; Laura G Sánchez-Lozada; David T Bonthron; Yuri Y Sautin; Richard J Johnson
Journal:  Proc Natl Acad Sci U S A       Date:  2012-02-27       Impact factor: 11.205

3.  PGK1 is a new member of the protein kinome.

Authors:  Xinjian Li; Yanhua Zheng; Zhimin Lu
Journal:  Cell Cycle       Date:  2016-04-22       Impact factor: 4.534

4.  A splicing switch from ketohexokinase-C to ketohexokinase-A drives hepatocellular carcinoma formation.

Authors:  Xinjian Li; Xu Qian; Li-Xia Peng; Yuhui Jiang; David H Hawke; Yanhua Zheng; Yan Xia; Jong-Ho Lee; Gilbert Cote; Hongxia Wang; Liwei Wang; Chao-Nan Qian; Zhimin Lu
Journal:  Nat Cell Biol       Date:  2016-04-18       Impact factor: 28.824

5.  Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis.

Authors:  Xinjian Li; Yuhui Jiang; Jill Meisenhelder; Weiwei Yang; David H Hawke; Yanhua Zheng; Yan Xia; Kenneth Aldape; Jie He; Tony Hunter; Liwei Wang; Zhimin Lu
Journal:  Mol Cell       Date:  2016-03-03       Impact factor: 17.970

6.  Molecular basis of essential fructosuria: molecular cloning and mutational analysis of human ketohexokinase (fructokinase).

Authors:  D T Bonthron; N Brady; I A Donaldson; B Steinmann
Journal:  Hum Mol Genet       Date:  1994-09       Impact factor: 6.150

7.  PKM2 functions as a histone kinase.

Authors:  Zhimin Lu
Journal:  Cell Cycle       Date:  2012-10-15       Impact factor: 4.534
  7 in total
  14 in total

1.  Genome-Wide CRISPR Screen for Essential Cell Growth Mediators in Mutant KRAS Colorectal Cancers.

Authors:  Edwin H Yau; Indrasena Reddy Kummetha; Gianluigi Lichinchi; Rachel Tang; Yunlin Zhang; Tariq M Rana
Journal:  Cancer Res       Date:  2017-09-27       Impact factor: 12.701

Review 2.  Metabolic Kinases Moonlighting as Protein Kinases.

Authors:  Zhimin Lu; Tony Hunter
Journal:  Trends Biochem Sci       Date:  2018-02-17       Impact factor: 13.807

Review 3.  Proteins moonlighting in tumor metabolism and epigenetics.

Authors:  Lei Lv; Qunying Lei
Journal:  Front Med       Date:  2021-01-02       Impact factor: 4.592

4.  Phosphoglycerate Kinase 1 Phosphorylates Beclin1 to Induce Autophagy.

Authors:  Xu Qian; Xinjian Li; Qingsong Cai; Chuanbao Zhang; Qiujing Yu; Yuhui Jiang; Jong-Ho Lee; David Hawke; Yugang Wang; Yan Xia; Yanhua Zheng; Bing-Hua Jiang; David X Liu; Tao Jiang; Zhimin Lu
Journal:  Mol Cell       Date:  2017-02-23       Impact factor: 17.970

5.  Choline Kinase Alpha2 Promotes Lipid Droplet Lipolysis in Non-Small-Cell Lung Carcinoma.

Authors:  Rongxuan Zhu; Yannan Yang; Fei Shao; Juhong Wang; Yibo Gao; Jie He; Zhimin Lu
Journal:  Front Oncol       Date:  2022-04-07       Impact factor: 5.738

6.  Conversion of PRPS Hexamer to Monomer by AMPK-Mediated Phosphorylation Inhibits Nucleotide Synthesis in Response to Energy Stress.

Authors:  Xu Qian; Xinjian Li; Lin Tan; Jong-Ho Lee; Yan Xia; Qingsong Cai; Yanhua Zheng; Hongxia Wang; Philip L Lorenzi; Zhimin Lu
Journal:  Cancer Discov       Date:  2017-10-26       Impact factor: 39.397

Review 7.  Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways.

Authors:  Marteinn T Snaebjornsson; Almut Schulze
Journal:  Exp Mol Med       Date:  2018-04-16       Impact factor: 8.718

8.  Role of Metabolism in Hepatic Stellate Cell Activation and Fibrogenesis.

Authors:  Wei Hou; Wing-Kin Syn
Journal:  Front Cell Dev Biol       Date:  2018-11-12

Review 9.  Nonmetabolic functions of metabolic enzymes in cancer development.

Authors:  Sean Lu; Yugang Wang
Journal:  Cancer Commun (Lond)       Date:  2018-10-26

10.  Metabolic features of cancer cells.

Authors:  Yugang Wang; Yan Xia; Zhimin Lu
Journal:  Cancer Commun (Lond)       Date:  2018-10-30
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