Literature DB >> 27356105

Resistance is not futile: Surviving Eg5 inhibition.

Megan E Dumas1, Emma G Sturgill1, Ryoma Ohi1.   

Abstract

Entities:  

Keywords:  Eg5; Kif15; anti-mitotic; chemotherapy; mitosis

Mesh：

Substances：

Year:  2016        PMID： 27356105      PMCID： PMC5105924          DOI： 10.1080/15384101.2016.1204864

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  7 in total

1.  The role of Hklp2 in the stabilization and maintenance of spindle bipolarity.

Authors:  David Vanneste; Masatoshi Takagi; Naoko Imamoto; Isabelle Vernos
Journal:  Curr Biol       Date:  2009-10-08       Impact factor: 10.834

2.  Kinesin-12 Kif15 targets kinetochore fibers through an intrinsic two-step mechanism.

Authors:  Emma G Sturgill; Dibyendu Kumar Das; Yoshimasa Takizawa; Yongdae Shin; Scott E Collier; Melanie D Ohi; Wonmuk Hwang; Matthew J Lang; Ryoma Ohi
Journal:  Curr Biol       Date:  2014-09-25       Impact factor: 10.834

3.  Nuclear envelope-associated dynein drives prophase centrosome separation and enables Eg5-independent bipolar spindle formation.

Authors:  Jonne A Raaijmakers; Roy G H P van Heesbeen; Johnathan L Meaders; Erica F Geers; Belen Fernandez-Garcia; René H Medema; Marvin E Tanenbaum
Journal:  EMBO J       Date:  2012-10-02       Impact factor: 11.598

4.  Kinesin-12 differentially affects spindle assembly depending on its microtubule substrate.

Authors:  Emma G Sturgill; Ryoma Ohi
Journal:  Curr Biol       Date:  2013-06-20       Impact factor: 10.834

5.  Kif15 cooperates with eg5 to promote bipolar spindle assembly.

Authors:  Marvin E Tanenbaum; Libor Macůrek; Aniek Janssen; Erica F Geers; Mónica Alvarez-Fernández; René H Medema
Journal:  Curr Biol       Date:  2009-10-08       Impact factor: 10.834

6.  Using transcriptome sequencing to identify mechanisms of drug action and resistance.

Authors:  Sarah A Wacker; Benjamin R Houghtaling; Olivier Elemento; Tarun M Kapoor
Journal:  Nat Chem Biol       Date:  2012-02-12       Impact factor: 15.040

7.  Kinesin-5 inhibitor resistance is driven by kinesin-12.

Authors:  Emma G Sturgill; Stephen R Norris; Yan Guo; Ryoma Ohi
Journal:  J Cell Biol       Date:  2016-04-18       Impact factor: 10.539
  7 in total
  4 in total

1.  Suppressor Analysis Uncovers That MAPs and Microtubule Dynamics Balance with the Cut7/Kinesin-5 Motor for Mitotic Spindle Assembly in Schizosaccharomyces pombe.

Authors:  Masashi Yukawa; Yusuke Yamada; Takashi Toda
Journal:  G3 (Bethesda)       Date:  2019-01-09       Impact factor: 3.154

2.  A microtubule polymerase cooperates with the kinesin-6 motor and a microtubule cross-linker to promote bipolar spindle assembly in the absence of kinesin-5 and kinesin-14 in fission yeast.

Authors:  Masashi Yukawa; Tomoki Kawakami; Masaki Okazaki; Kazunori Kume; Ngang Heok Tang; Takashi Toda
Journal:  Mol Biol Cell       Date:  2017-10-11       Impact factor: 4.138

Review 3.  How Essential Kinesin-5 Becomes Non-Essential in Fission Yeast: Force Balance and Microtubule Dynamics Matter.

Authors:  Masashi Yukawa; Yasuhiro Teratani; Takashi Toda
Journal:  Cells       Date:  2020-05-07       Impact factor: 6.600

4.  HSP70 regulates Eg5 distribution within the mitotic spindle and modulates the cytotoxicity of Eg5 inhibitors.

Authors:  Chieh-Ting Fang; Hsiao-Hui Kuo; Shao-Chun Hsu; Ling-Huei Yih
Journal:  Cell Death Dis       Date:  2020-09-01       Impact factor: 8.469
  4 in total

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