Literature DB >> 27355871

Gallium and Functionalized-Porphyrins Combine to Form Potential Lysosome-Specific Multimodal Bioprobes.

Jie Pan1, Bethany I Harriss2, Chi-Fai Chan1, Lijun Jiang1, Tik-Hung Tsoi3, Nicholas J Long2, Wing-Tak Wong3, Wai-Kwok Wong1, Ka-Leung Wong1.   

Abstract

A water-soluble bimetallic normal ("cold") and radiochemical ("hot") gallium-porphyrin-ruthenium-bipyridine complex (GaporRu-1) has been synthesized by microwave methodology in short reaction times with good (>85%) yields. (68)GaporRu-1 is demonstrated to be a potential multimodal and functional bioprobe for positron emission tomography (PET), lysosome specific optical imaging, and photodynamic therapy.

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Year:  2016        PMID: 27355871     DOI: 10.1021/acs.inorgchem.6b01159

Source DB:  PubMed          Journal:  Inorg Chem        ISSN: 0020-1669            Impact factor:   5.165


  1 in total

Review 1.  Porphyrins as Chelating Agents for Molecular Imaging in Nuclear Medicine.

Authors:  Krystyna Pyrzynska; Krzysztof Kilian; Mateusz Pęgier
Journal:  Molecules       Date:  2022-05-21       Impact factor: 4.927

  1 in total

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