Literature DB >> 27354328

Osteoporosis: The Result of an 'Aged' Bone Microenvironment.

Bo Yu1, Cun-Yu Wang2.   

Abstract

Osteoporosis is an age-related progressive bone disease. Recent advances in epigenetics, cell biology, osteoimmunology, and genetic epidemiology have unraveled new mechanisms and players underlying the pathology of osteoporosis, supporting a model of age-related dysregulation and crosstalk in the bone microenvironment.
Copyright © 2016 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Wnt signaling; aging; epigenetics; osteoimmunology; osteoporosis

Mesh：

Year:  2016        PMID： 27354328      PMCID： PMC4969144          DOI： 10.1016/j.molmed.2016.06.002

Source DB:  PubMed          Journal:  Trends Mol Med        ISSN： 1471-4914            Impact factor:   11.951


  15 in total

Review 1.  Emerging therapeutic opportunities for skeletal restoration.

Authors:  Masanobu Kawai; Ulrike I Mödder; Sundeep Khosla; Clifford J Rosen
Journal:  Nat Rev Drug Discov       Date:  2011-02       Impact factor: 84.694

Review 2.  The genetics of bone mass and susceptibility to bone diseases.

Authors:  David Karasik; Fernando Rivadeneira; Mark L Johnson
Journal:  Nat Rev Rheumatol       Date:  2016-04-07       Impact factor: 20.543

3.  Sclerostin inhibition promotes TNF-dependent inflammatory joint destruction.

Authors:  Corinna Wehmeyer; Svetlana Frank; Denise Beckmann; Martin Böttcher; Christoph Cromme; Ulrich König; Michelle Fennen; Annelena Held; Peter Paruzel; Christine Hartmann; Athanasios Stratis; Adelheid Korb-Pap; Thomas Kamradt; Ina Kramer; Wim van den Berg; Michaela Kneissel; Thomas Pap; Berno Dankbar
Journal:  Sci Transl Med       Date:  2016-03-16       Impact factor: 17.956

4.  T cell costimulation molecules CD80/86 inhibit osteoclast differentiation by inducing the IDO/tryptophan pathway.

Authors:  Aline Bozec; Mario M Zaiss; Rosebeth Kagwiria; Reinhard Voll; Manfred Rauh; Zhu Chen; Sandra Mueller-Schmucker; Richard A Kroczek; Lucie Heinzerling; Muriel Moser; Andrew L Mellor; Jean-Pierre David; Georg Schett
Journal:  Sci Transl Med       Date:  2014-05-07       Impact factor: 17.956

5.  Inflammatory markers and risk of hip fracture in older white women: the study of osteoporotic fractures.

Authors:  Kamil E Barbour; Li-Yung Lui; Kristine E Ensrud; Teresa A Hillier; Erin S LeBlanc; Steven W Ing; Marc C Hochberg; Jane A Cauley
Journal:  J Bone Miner Res       Date:  2014-09       Impact factor: 6.741

6.  Age-related intrinsic changes in human bone-marrow-derived mesenchymal stem cells and their differentiation to osteoblasts.

Authors:  Shuanhu Zhou; Joel S Greenberger; Michael W Epperly; Julie P Goff; Carolyn Adler; Meryl S Leboff; Julie Glowacki
Journal:  Aging Cell       Date:  2008-01-31       Impact factor: 9.304

7.  The unitary model for estrogen deficiency and the pathogenesis of osteoporosis: is a revision needed?

Authors:  Sundeep Khosla; L Joseph Melton; B Lawrence Riggs
Journal:  J Bone Miner Res       Date:  2011-03       Impact factor: 6.741

8.  Inhibition of osteoblastic bone formation by nuclear factor-kappaB.

Authors:  Jia Chang; Zhuo Wang; Eric Tang; Zhipeng Fan; Laurie McCauley; Renny Franceschi; Kunliang Guan; Paul H Krebsbach; Cun-Yu Wang
Journal:  Nat Med       Date:  2009-06       Impact factor: 53.440

9.  Histone demethylase JMJD3 is required for osteoblast differentiation in mice.

Authors:  Feng Zhang; Longyong Xu; Longxia Xu; Qing Xu; Gerard Karsenty; Charlie Degui Chen
Journal:  Sci Rep       Date:  2015-08-25       Impact factor: 4.379

10.  PDGF-BB secreted by preosteoclasts induces angiogenesis during coupling with osteogenesis.

Authors:  Hui Xie; Zhuang Cui; Long Wang; Zhuying Xia; Yin Hu; Lingling Xian; Changjun Li; Liang Xie; Janet Crane; Mei Wan; Gehua Zhen; Qin Bian; Bin Yu; Weizhong Chang; Tao Qiu; Maureen Pickarski; Le Thi Duong; Jolene J Windle; Xianghang Luo; Eryuan Liao; Xu Cao
Journal:  Nat Med       Date:  2014-10-05       Impact factor: 53.440
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  33 in total

Review 1.  Mesenchymal Stem Cells in the Musculoskeletal System: From Animal Models to Human Tissue Regeneration?

Authors:  Klemen Čamernik; Ariana Barlič; Matej Drobnič; Janja Marc; Matjaž Jeras; Janja Zupan
Journal:  Stem Cell Rev Rep       Date:  2018-06       Impact factor: 5.739

Review 2.  Defining osteoblast and adipocyte lineages in the bone marrow.

Authors:  J L Pierce; D L Begun; J J Westendorf; M E McGee-Lawrence
Journal:  Bone       Date:  2018-05-18       Impact factor: 4.398

3.  A novel long noncoding RNA PGC1β-OT1 regulates adipocyte and osteoblast differentiation through antagonizing miR-148a-3p.

Authors:  Hairui Yuan; Xiaowei Xu; Xue Feng; Endong Zhu; Jie Zhou; Guannan Wang; Lijie Tian; Baoli Wang
Journal:  Cell Death Differ       Date:  2019-02-06       Impact factor: 15.828

Review 4.  Extracellular Vesicles in Bone Homeostasis: Emerging Mediators of Osteoimmune Interactions and Promising Therapeutic Targets.

Authors:  Xiaoyuan Huang; Yanhua Lan; Jiahui Shen; Zhuo Chen; Zhijian Xie
Journal:  Int J Biol Sci       Date:  2022-06-21       Impact factor: 10.750

Review 5.  Osteoporosis and periodontal diseases - An update on their association and mechanistic links.

Authors:  Bo Yu; Cun-Yu Wang
Journal:  Periodontol 2000       Date:  2022-03-04       Impact factor: 12.239

6.  Loss of KDM4B exacerbates bone-fat imbalance and mesenchymal stromal cell exhaustion in skeletal aging.

Authors:  Peng Deng; Quan Yuan; Yingduan Cheng; Jiong Li; Zhenqing Liu; Yan Liu; Ye Li; Trent Su; Jing Wang; Mari Ekimyan Salvo; Weiguang Wang; Guoping Fan; Karen Lyons; Bo Yu; Cun-Yu Wang
Journal:  Cell Stem Cell       Date:  2021-02-10       Impact factor: 25.269

7.  Age-associated callus senescent cells produce TGF-β1 that inhibits fracture healing in aged mice.

Authors:  Jiatong Liu; Jun Zhang; Xi Lin; Brendan F Boyce; Hengwei Zhang; Lianping Xing
Journal:  J Clin Invest       Date:  2022-04-15       Impact factor: 19.456

8.  Bi-directional regulation functions of lanthanum-substituted layered double hydroxide nanohybrid scaffolds via activating osteogenesis and inhibiting osteoclastogenesis for osteoporotic bone regeneration.

Authors:  Min Chu; Zhenyu Sun; Zhanghao Fan; Degang Yu; Yuanqing Mao; Yaping Guo
Journal:  Theranostics       Date:  2021-05-03       Impact factor: 11.556

9.  CGRP Regulates the Age-Related Switch Between Osteoblast and Adipocyte Differentiation.

Authors:  Hang Li; Jian Qu; Haihong Zhu; Jiaojiao Wang; Hao He; Xinyan Xie; Ren Wu; Qiong Lu
Journal:  Front Cell Dev Biol       Date:  2021-05-26

10.  PGC-1α Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ.

Authors:  Bo Yu; Lihong Huo; Yunsong Liu; Peng Deng; John Szymanski; Jiong Li; Xianghang Luo; Christine Hong; Jiandie Lin; Cun-Yu Wang
Journal:  Cell Stem Cell       Date:  2018-07-12       Impact factor: 25.269
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