Xin Yan Liu1, Li Li1, Jia Qing Xiao2, Chang Zhi He3, Xiu Lin Lyu4, Lei Gao1, Xiao Wei Yang5, Xin Gang Cui5, Li Hua Fan1. 1. College of Public Health, Harbin Medical University, Harbin 150086, Heilongjiang, China. 2. Heilongjiang Provincial Center for Disease Control and Prevention, Harbin 150040, Heilongjiang, China. 3. College of Management for the postgraduate, Harbin Medical University, Harbin 150086, Heilongjiang, China. 4. Heilongjiang Provincial Hospital, Harbin 150040, Heilongjiang, China. 5. Department of Public Health, Mudanjiang Medical College, Mudanjiang 157000, Heilongjiang, China.
Abstract
OBJECTIVE: We investigated the feasibility and efficacy of cognitive training for older adults in rural settings and with low education levels, who have mild cognitive impairment (MCI). METHODS:Forty-five older adults (ages >65 years) with MCI were assigned to treatment or control groups, at a 2:1 ratio. Cognitive training occurred in the treatment group for 2 months. The cognitive abilities of the participants were assessed at pre-training, metaphase, and post-training time points, using the Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Loewenstein Occupational Therapy Cognitive Assessment (LOTCA), and Hamilton Depression Scale (HAM-D). RESULTS: Following training, cognitive abilities improved in the treatment group, based on the total scores of all 4 measures, as well as specifically on the MoCA and LOTCA. There were differences in the main effects of group and time point on some subscales, but these differences had little, if any, effect on the overall analyses. CONCLUSION: The present study demonstrated that cognitive training has beneficial effects on attention, language, orientation, visual perception, organization of visual movement, and logical questioning in patients with MCI. Furthermore, the observed effects are long-term changes.
RCT Entities:
OBJECTIVE: We investigated the feasibility and efficacy of cognitive training for older adults in rural settings and with low education levels, who have mild cognitive impairment (MCI). METHODS: Forty-five older adults (ages >65 years) with MCI were assigned to treatment or control groups, at a 2:1 ratio. Cognitive training occurred in the treatment group for 2 months. The cognitive abilities of the participants were assessed at pre-training, metaphase, and post-training time points, using the Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Loewenstein Occupational Therapy Cognitive Assessment (LOTCA), and Hamilton Depression Scale (HAM-D). RESULTS: Following training, cognitive abilities improved in the treatment group, based on the total scores of all 4 measures, as well as specifically on the MoCA and LOTCA. There were differences in the main effects of group and time point on some subscales, but these differences had little, if any, effect on the overall analyses. CONCLUSION: The present study demonstrated that cognitive training has beneficial effects on attention, language, orientation, visual perception, organization of visual movement, and logical questioning in patients with MCI. Furthermore, the observed effects are long-term changes.
Authors: Zhenren Peng; Hu Jiang; Xiaomin Wang; Kaiyong Huang; Yukun Zuo; Xiangmin Wu; Abu S Abdullah; Li Yang Journal: Biomed Res Int Date: 2019-11-30 Impact factor: 3.246