Giovanni Targher1, Christopher D Byrne2. 1. Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Verona, and at Azienda Ospedaliera Universitaria Integrata, Piazzale Aristide Stefani 1, Verona 37126, Italy. 2. Nutrition and Metabolism, Faculty of Medicine, University of Southampton; and Southampton National Institute for Health Research Biomedical Research Centre, University Hospital Southampton, Tremona Road, Southampton SO166YD, UK.