| Literature DB >> 27353022 |
Jean-François Faucher1, David Morquin2, Jacques Reynes3, Catherine Chirouze4, Bruno Hoen5, Vincent Le Moing6.
Abstract
Liposomal amphotericin B (LAmb) may fail to heal Leishmania infantum visceral leishmaniasis (VL) in the immunodeficient host. There are currently no guidelines on how to treat such patients and efficacy of miltefosine monotherapy seems limited in this indication. We present 2 cases of patients with VL and AIDS for which LAmb had to be interrupted (one because of toxicity, one because of treatment failure) and who were treated effectively with pentamidine followed by miltefosine.Entities:
Keywords: Aids; Liposomal amphotericin B; Miltefosine; Pentamidine; Visceral leishmaniasis
Mesh：
Substances：
Year: 2016 PMID： 27353022 DOI： 10.1016/j.parint.2016.06.009
Source DB: PubMed Journal: Parasitol Int ISSN： 1383-5769 Impact factor: 2.230