Literature DB >> 2735116

[Changes in the parameters of locomotion following partial extirpation of the motor cortex in white rats].

D N Lenkov, N I Vereshchak.   

Abstract

Quantitative locomotion changes have been studied in the norm and in different periods after local ablation of motor projection of hind paw in the right hemisphere of 5-16 weeks white rats. The length and width of step gradually increase with the age, and coefficients of gait asymmetry reflecting individual characteristics, are relatively stable in intact animals. Local decortication is accompanied by significant shifts of all locomotion parameters clearly expressed in the first days after ablation. The most sensitive characteristic of gait anomaly is the standard deviation of half-step. In 5 weeks after ablation a lag is observed of operated rats behind the control ones in all parameters. Load application contributes to revealing of locomotion parameters shifts from the norm in later periods after decortication. In 9 and 11 weeks after surgery, the signs of supercompensation are observed in a number of parameters.

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Year:  1989        PMID: 2735116

Source DB:  PubMed          Journal:  Zh Vyssh Nerv Deiat Im I P Pavlova        ISSN: 0044-4677            Impact factor:   0.437


  3 in total

1.  Restoration of locomotion in white rats after multiple lesioning of the motor cortex and heterotopic transplantation of cortex fragments.

Authors:  N I Vereshchak; D N Lenkov
Journal:  Neurosci Behav Physiol       Date:  1998 Nov-Dec

2.  The restoration of locomotion following double ablations of the motor cortex and heterotopic transplantation of cortical tissue in the white rat.

Authors:  N I Vereshchak
Journal:  Neurosci Behav Physiol       Date:  1993 May-Jun

3.  The recovery of locomotion following partial extirpation of the motor cortex and transplantation of cortical tissue in the white rat.

Authors:  N I Vereshchak; D N Lenkov
Journal:  Neurosci Behav Physiol       Date:  1990 Jul-Aug
  3 in total

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