Literature DB >> 27350442

Rewiring macrophages for anti-tumour immunity.

Yunqin Lee1, Subhra K Biswas1.   

Abstract

Tumour-associated macrophages facilitate cancer progression, but whether they can be reprogrammed to elicit an anti-tumour response remains unclear. Deletion of the microRNA-processing enzyme Dicer is now shown to rewire macrophages to an anti-tumour mode, leading to an enhanced response to immunotherapy and inhibition of tumour progression.

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Year:  2016        PMID： 27350442     DOI： 10.1038/ncb3384

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  15 in total

Review 1.  Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm.

Authors:  Subhra K Biswas; Alberto Mantovani
Journal:  Nat Immunol       Date:  2010-09-20       Impact factor: 25.606

2.  New insights into the multidimensional concept of macrophage ontogeny, activation and function.

Authors:  Florent Ginhoux; Joachim L Schultze; Peter J Murray; Jordi Ochando; Subhra K Biswas
Journal:  Nat Immunol       Date:  2016-01       Impact factor: 25.606

3.  Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage.

Authors:  Sergei B Koralov; Stefan A Muljo; Gunther R Galler; Azra Krek; Tirtha Chakraborty; Chryssa Kanellopoulou; Kari Jensen; Bradley S Cobb; Matthias Merkenschlager; Nikolaus Rajewsky; Klaus Rajewsky
Journal:  Cell       Date:  2008-03-07       Impact factor: 41.582

4.  Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes.

Authors:  Kiavash Movahedi; Damya Laoui; Conny Gysemans; Martijn Baeten; Geert Stangé; Jan Van den Bossche; Matthias Mack; Daniel Pipeleers; Peter In't Veld; Patrick De Baetselier; Jo A Van Ginderachter
Journal:  Cancer Res       Date:  2010-06-22       Impact factor: 12.701

5.  miR-511-3p modulates genetic programs of tumor-associated macrophages.

Authors:  Mario Leonardo Squadrito; Ferdinando Pucci; Laura Magri; Davide Moi; Gregor D Gilfillan; Anna Ranghetti; Andrea Casazza; Massimiliano Mazzone; Robert Lyle; Luigi Naldini; Michele De Palma
Journal:  Cell Rep       Date:  2012-02-09       Impact factor: 9.423

6.  Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors.

Authors:  Michele De Palma; Mary Anna Venneri; Rossella Galli; Lucia Sergi Sergi; Letterio S Politi; Maurilio Sampaolesi; Luigi Naldini
Journal:  Cancer Cell       Date:  2005-09       Impact factor: 31.743

Review 7.  Tumor-associated macrophages: from mechanisms to therapy.

Authors:  Roy Noy; Jeffrey W Pollard
Journal:  Immunity       Date:  2014-07-17       Impact factor: 31.745

8.  Genomic DNA copy-number alterations of the let-7 family in human cancers.

Authors:  Yanling Wang; Xiaowen Hu; Joel Greshock; Liang Shen; Xiaojun Yang; Zhongjun Shao; Shun Liang; Janos L Tanyi; Anil K Sood; Lin Zhang
Journal:  PLoS One       Date:  2012-09-06       Impact factor: 3.240

9.  A role for Dicer in immune regulation.

Authors:  Bradley S Cobb; Arnulf Hertweck; James Smith; Eric O'Connor; Daniel Graf; Terence Cook; Stephen T Smale; Shimon Sakaguchi; Frederick J Livesey; Amanda G Fisher; Matthias Merkenschlager
Journal:  J Exp Med       Date:  2006-10-23       Impact factor: 14.307

10.  Transformation of the tumour microenvironment by a CD40 agonist antibody correlates with improved responses to PD-L1 blockade in a mouse orthotopic pancreatic tumour model.

Authors:  Nadia M Luheshi; Jane Coates-Ulrichsen; James Harper; Stefanie Mullins; Michal G Sulikowski; Philip Martin; Lee Brown; Arthur Lewis; Gareth Davies; Michelle Morrow; Robert W Wilkinson
Journal:  Oncotarget       Date:  2016-04-05
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