| Literature DB >> 27349966 |
Guoliang Yu1, Ye Liang1, Ziming Huang1,2, Deron W Jones1, Kirkwood A Pritchard1, Hao Zhang3.
Abstract
Entities:
Year: 2016 PMID: 27349966 PMCID: PMC4924260 DOI: 10.1186/s12974-016-0639-y
Source DB: PubMed Journal: J Neuroinflammation ISSN: 1742-2094 Impact factor: 8.322
Fig. 1KYC significantly reduced neurological deficit and brain infarct size in mice subjected to MCAO. a Effects of KYC on neurological severity scores during 7 days after MCAO. Top panel: Experimental scheme; KYC (10 mg/kg/day) or PBS via i.p. was administrated starting 1 h after reperfusion. Bottom panel: Neurological severity scores of mice after MCAO (*p < 0.05, KYC vs. PBS group at same time interval, nonparametric Mann–Whitney test); b Effect of KYC on infarct size in mice 3 days after MCAO. Images of brain coronal sections (20-μm thick, 1-mm interval from rostral to caudal) by cresyl violet stain were shown; c Infarct volume (*p < 0.05, KYC vs. PBS group, n = 5/group, t test)