Sheng-Han Tsai1, Jia-Hwia Wang2, Yi-Chen Lai3, Yen-Hwa Chang4, Hsiao-Jen Chung4, Luke S Chang5. 1. Department of Urology, Cheng-Hsin General Hospital, Taipei, Taiwan, ROC. 2. Department of Radiology, Cheng-Hsin General Hospital, Taipei, Taiwan, ROC; National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC. Electronic address: ch9400@chgh.org.tw. 3. National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC; Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC. 4. National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC; Department of Urology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC. 5. Department of Urology, Cheng-Hsin General Hospital, Taipei, Taiwan, ROC; National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC.
Abstract
BACKGROUND: Mixed epithelial and stromal tumor of the kidney (MESTK) is a rare tumor, with few malignant cases reported. Occurring mostly in middle-aged women, it is characterized by a biphasic pathological structure. METHODS: This study retrospectively reviewed the imaging findings and medical records of six MESTK cases of a single institution in a 10-year period. RESULTS: All of the patients were middle-aged women without hormone therapy history. The typical image was a renal tumor with varied cystic components. Half of the cases had sinus invagination, but only one had intratumor calcification. On imaging studies, four were Bosniak Category IV, one was Category III, and one presented as a solid tumor. The mean RENAL nephrometry score was 9.3. Five patients underwent partial nephrectomy, with no statistical renal functional deterioration after nephron-sparing surgery. There were no peri-operative complications. CONCLUSION: Surgery remains the treatment of choice for MESTK, and nephron-sparing surgery should be considered in feasible cases.
BACKGROUND: Mixed epithelial and stromal tumor of the kidney (MESTK) is a rare tumor, with few malignant cases reported. Occurring mostly in middle-aged women, it is characterized by a biphasic pathological structure. METHODS: This study retrospectively reviewed the imaging findings and medical records of six MESTK cases of a single institution in a 10-year period. RESULTS: All of the patients were middle-aged women without hormone therapy history. The typical image was a renal tumor with varied cystic components. Half of the cases had sinus invagination, but only one had intratumor calcification. On imaging studies, four were Bosniak Category IV, one was Category III, and one presented as a solid tumor. The mean RENAL nephrometry score was 9.3. Five patients underwent partial nephrectomy, with no statistical renal functional deterioration after nephron-sparing surgery. There were no peri-operative complications. CONCLUSION: Surgery remains the treatment of choice for MESTK, and nephron-sparing surgery should be considered in feasible cases.
Authors: Cathy D Vocke; Christopher J Ricketts; Mark W Ball; Laura S Schmidt; Adam R Metwalli; Lindsay A Middelton; J Keith Killian; Javed Khan; Paul S Meltzer; William F Simonds; Maria J Merino; W Marston Linehan Journal: Urology Date: 2018-11-16 Impact factor: 2.649