| Literature DB >> 27346609 |
Huijun Phoebe Tham1, Hongzhong Chen2, Yu Hui Tan2, Qiuyu Qu2, Sivaramapanicker Sreejith2, Lingzhi Zhao2, Subbu S Venkatraman3, Yanli Zhao4.
Abstract
Silylated zinc phthalocyanine (ZnPc) was anchored onto silica-coated gold nanorods (AuNR) with retained local surface plasmon resonance (LSPR). Independent LSPR and singlet oxygen production of anchored ZnPc enhance the photothermal and photodynamic efficacy of the obtained AuNR-Si-ZnPc under NIR light excitation. AuNR-Si-ZnPc was further grafted with hyaluronic acid (HA). Since HA has selective targeting capability to CD44 antigens, the final hybrid could target cancer cells directly for synergistic photothermal and photodynamic therapy.Entities:
Year: 2016 PMID: 27346609 DOI: 10.1039/c6cc03076a
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222