| Literature DB >> 27346565 |
Andrea Piccin1,2,3, Angela Maria Di Pierro1,2,3,4, Mario Tagnin2,5, Carla Russo2,6, Roland Fustos2,6, Daisy Corvetta1,2,7, Marco Primerano2,8, Elena Magri9, Viviana Conci2,5, Ivo Gentilini10, Evelyn Burkia Stocker1,2, Giovanni Negri2,7, Guido Mazzoleni2,7, Günther Gastl3, Fabrizio Fontanella2,5.
Abstract
AIM: Bone osteoradionecrosis is a serious complication of radiation treatment. Current treatment approaches are not curative and treatment response is often poor leading to high social and healthcare costs. CASE REPORT: We report on the first case of osteoradionecrosis with successful restitutio ab integro by repeated administration of platelet gel (PLT-gel) and surgery in a critically ill patient. The administration of PLT-gel during a severe septic episode helped regeneration of bone and soft tissues, shortening the hospital stay of the patient. It was also noted that following applications of PLT-gel, both the use of morphine and the numbers of infective episodes were reduced.Entities:
Keywords: plastic surgery; platelet gel; platelet-rich plasma; radiodermatitis
Mesh：
Substances：
Year: 2016 PMID： 27346565 DOI： 10.2217/rme-2016-0031
Source DB: PubMed Journal: Regen Med ISSN： 1746-0751 Impact factor: 3.806