Literature DB >> 27345989

Generation of iPSC line iPSC-FH2.1 in hypoxic conditions from human foreskin fibroblasts.

María Questa1, Leonardo Romorini2, Carolina Blüguermann3, Claudia María Solari4, Gabriel Neiman3, Carlos Luzzani3, María Élida Scassa3, Gustavo Emilio Sevlever3, Alejandra Sonia Guberman5, Santiago Gabriel Miriuka2.   

Abstract

Human foreskin fibroblasts were used to generate the iPSC line iPSC-FH2.1 using the EF1a-hSTEMCCA-loxP vector expressing OCT4, SOX2, c-MYC and KLF4, in 5% O2 culture conditions. Stemness was confirmed, as was pluripotency both in vivo and in vitro, in normoxia and hypoxia. Human Embryonic Stem Cell (hESC) line WA-09 and reprogrammed fibroblast primary culture HFF-FM were used as controls.
Copyright © 2015 University of Texas at Austin Dell Medical School. Published by Elsevier B.V. All rights reserved.

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Year:  2016        PMID： 27345989     DOI： 10.1016/j.scr.2015.12.026

Source DB:  PubMed          Journal:  Stem Cell Res        ISSN： 1873-5061            Impact factor:   2.020


  11 in total

1.  Protocol for morphometric analysis of neurons derived from human pluripotent stem cells.

Authors:  Sofía Mucci; María Soledad Rodriguez-Varela; Luciana Isaja; Sofía Luján Ferriol-Laffouillere; Gustavo Emilio Sevlever; María Elida Scassa; Leonardo Romorini
Journal:  STAR Protoc       Date:  2022-06-18

2.  Regulation of cyclin E1 expression in human pluripotent stem cells and derived neural progeny.

Authors:  María Soledad Rodríguez Varela; Sofía Mucci; Guillermo Agustín Videla Richardson; Olivia Morris Hanon; Verónica Alejandra Furmento; Santiago Gabriel Miriuka; Gustavo Emilio Sevlever; María Elida Scassa; Leonardo Romorini
Journal:  Cell Cycle       Date:  2018-08-10       Impact factor: 4.534

3.  AKT/GSK3β signaling pathway is critically involved in human pluripotent stem cell survival.

Authors:  Leonardo Romorini; Ximena Garate; Gabriel Neiman; Carlos Luzzani; Verónica Alejandra Furmento; Alejandra Sonia Guberman; Gustavo Emilio Sevlever; María Elida Scassa; Santiago Gabriel Miriuka
Journal:  Sci Rep       Date:  2016-10-20       Impact factor: 4.379

4.  MicroRNA characterization in equine induced pluripotent stem cells.

Authors:  Lucia Natalia Moro; Guadalupe Amin; Veronica Furmento; Ariel Waisman; Ximena Garate; Gabriel Neiman; Alejandro La Greca; Natalia Lucia Santín Velazque; Carlos Luzzani; Gustavo E Sevlever; Gabriel Vichera; Santiago Gabriel Miriuka
Journal:  PLoS One       Date:  2018-12-03       Impact factor: 3.240

5.  Deep Learning Neural Networks Highly Predict Very Early Onset of Pluripotent Stem Cell Differentiation.

Authors:  Ariel Waisman; Alejandro La Greca; Alan M Möbbs; María Agustina Scarafía; Natalia L Santín Velazque; Gabriel Neiman; Lucía N Moro; Carlos Luzzani; Gustavo E Sevlever; Alejandra S Guberman; Santiago G Miriuka
Journal:  Stem Cell Reports       Date:  2019-03-14       Impact factor: 7.765

6.  Single cell transfection of human-induced pluripotent stem cells using a droplet-based microfluidic system.

Authors:  Camilo Pérez-Sosa; Anahí Sanluis-Verdes; Ariel Waisman; Antonella Lombardi; Gustavo Rosero; Alejandro La Greca; Shekhar Bhansali; Natalia Bourguignon; Carlos Luzzani; Maximiliano S Pérez; Santiago Miriuka; Betiana Lerner
Journal:  R Soc Open Sci       Date:  2022-01-12       Impact factor: 2.963

7.  Stable expression of a truncated TLX variant drives differentiation of induced pluripotent stem cells into self-renewing neural stem cells for production of extracellular vesicles.

Authors:  Mingzhi Xu; Gang Chen; Yanan Dong; Shensi Xiang; Miaomiao Xue; Yongxue Liu; Haijing Song; Haifeng Song; Yi Wang
Journal:  Stem Cell Res Ther       Date:  2022-09-02       Impact factor: 8.079

Review 8.  The Potential of iPSCs for the Treatment of Premature Aging Disorders.

Authors:  Claudia Compagnucci; Enrico Bertini
Journal:  Int J Mol Sci       Date:  2017-11-07       Impact factor: 5.923

9.  Extracellular vesicles from pluripotent stem cell-derived mesenchymal stem cells acquire a stromal modulatory proteomic pattern during differentiation.

Authors:  Alejandro La Greca; Claudia Solari; Veronica Furmento; Antonella Lombardi; Maria Celeste Biani; Cyntia Aban; Lucia Moro; Marcela García; Alejandra Sonia Guberman; Gustavo Emilio Sevlever; Santiago Gabriel Miriuka; Carlos Luzzani
Journal:  Exp Mol Med       Date:  2018-09-10       Impact factor: 8.718

10.  Chemical hypoxia induces apoptosis of human pluripotent stem cells by a NOXA-mediated HIF-1α and HIF-2α independent mechanism.

Authors:  Luciana Isaja; Sofía Mucci; Jonathan Vera; María Soledad Rodríguez-Varela; Mariela Marazita; Olivia Morris-Hanon; Guillermo Agustín Videla-Richardson; Gustavo Emilio Sevlever; María Elida Scassa; Leonardo Romorini
Journal:  Sci Rep       Date:  2020-11-26       Impact factor: 4.379
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