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Literature DB >> 27345395

STAT3 selectively interacts with Smad3 to antagonize TGF-β signalling.

G Wang, Y Yu, C Sun, T Liu, T Liang, L Zhan, X Lin, X-H Feng.

Abstract

Entities: Gene

Year: 2016 PMID： 27345395 DOI： 10.1038/onc.2016.145

Source DB: PubMed Journal: Oncogene ISSN： 0950-9232 Impact factor: 9.867

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Cited

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11 in total

1. AAV1.SERCA2a Gene Therapy Reverses Pulmonary Fibrosis by Blocking the STAT3/FOXM1 Pathway and Promoting the SNON/SKI Axis.

Authors: Malik Bisserier; Javier Milara; Yassine Abdeldjebbar; Sarah Gubara; Carly Jones; Carlos Bueno-Beti; Elena Chepurko; Erik Kohlbrenner; Michael G Katz; Sima Tarzami; Julio Cortijo; Jane Leopold; Roger J Hajjar; Yassine Sassi; Lahouaria Hadri
Journal: Mol Ther Date: 2019-12-06 Impact factor: 11.454

2. Opposite functions of STAT3 and Smad3 in regulating Tiam1 expression in Th17 cells.

Authors: Thomas Buttrick; Samia J Khoury; Wassim Elyaman
Journal: Small GTPases Date: 2017-09-18

3. Development of resistance to FAK inhibition in pancreatic cancer is linked to stromal depletion.

Authors: Hong Jiang; Xiuting Liu; Brett L Knolhoff; Samarth Hegde; Kyung Bae Lee; Hongmei Jiang; Ryan C Fields; Jonathan A Pachter; Kian-Huat Lim; David G DeNardo
Journal: Gut Date: 2019-05-10 Impact factor: 23.059

4. Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression.

Authors: Zhongchi Li; Vivien Low; Valbona Luga; Janet Sun; Ethan Earlie; Bobak Parang; Kripa Shobana Ganesh; Sungyun Cho; Jennifer Endress; Tanya Schild; Mengying Hu; David Lyden; Wenbing Jin; Chunjun Guo; Noah Dephoure; Lewis C Cantley; Ashley M Laughney; John Blenis
Journal: Nat Commun Date: 2022-10-20 Impact factor: 17.694

5. IL-37 suppresses hepatocellular carcinoma growth by converting pSmad3 signaling from JNK/pSmad3L/c-Myc oncogenic signaling to pSmad3C/P21 tumor-suppressive signaling.

Authors: Rui Liu; Chengyong Tang; Ai Shen; Huating Luo; Xufu Wei; Daofeng Zheng; Chao Sun; Zhongtang Li; Di Zhu; Tingting Li; Zhongjun Wu
Journal: Oncotarget Date: 2016-12-20

Review 10. Insulin/IGF-1 signaling promotes immunosuppression via the STAT3 pathway: impact on the aging process and age-related diseases.

Authors: Antero Salminen; Kai Kaarniranta; Anu Kauppinen
Journal: Inflamm Res Date: 2021-09-02 Impact factor: 4.575

STAT3 selectively interacts with Smad3 to antagonize TGF-β signalling.

1. AAV1.SERCA2a Gene Therapy Reverses Pulmonary Fibrosis by Blocking the STAT3/FOXM1 Pathway and Promoting the SNON/SKI Axis.

2. Opposite functions of STAT3 and Smad3 in regulating Tiam1 expression in Th17 cells.

3. Development of resistance to FAK inhibition in pancreatic cancer is linked to stromal depletion.

4. Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression.

5. IL-37 suppresses hepatocellular carcinoma growth by converting pSmad3 signaling from JNK/pSmad3L/c-Myc oncogenic signaling to pSmad3C/P21 tumor-suppressive signaling.

6. STAT3 is a master regulator of epithelial identity and KRAS-driven tumorigenesis.

7. GNAS promotes inflammation-related hepatocellular carcinoma progression by promoting STAT3 activation.

8. STAT3 is critical for skeletal development and bone homeostasis by regulating osteogenesis.

Review 9. STAT3 in Skeletal Muscle Function and Disorders.

Review 10. Insulin/IGF-1 signaling promotes immunosuppression via the STAT3 pathway: impact on the aging process and age-related diseases.