Literature DB >> 27345086

Evaluating the effect of a haemoglobin spray on size reduction in chronic DFUs: clinical outcomes at 12 weeks.

Sharon Dawn Hunt1, Samantha Haycocks2, Joanne McCardle3, Karl Guttormsen4.   

Abstract

A recent multi-centre observational evaluation investigated the effect of a topical haemoglobin spray (Granulox, Infirst), used as an adjunct to standard care, on wound size reduction in 17 patients (4 females/13 males) with 20 chronic diabetic foot ulcers (DFUs) over a 4-week period. In 14 of the 18 wounds that completed the evaluation (one patient dropped out due to an infection) there was a mean reduction of 53.8% (range: 11.9-100%). The product was acceptable to both patients and clinicians, who all found it easy to use. This article describes the outcomes for the remaining 13 patients (with 15 wounds) who continued using the spray after the 4-week evaluation ended. (Data are not available for two patients and the one patient who healed during the 4-week evaluation.) By 12 weeks, three wounds (20%) had healed, eight (53%) were progressing towards healing, three (20%) increased in size and one (7%) was slow healing.

Entities:  

Keywords:  Diabetic foot ulcer; Patient and clinician satisfaction; Slough reduction; Topical haemoglobin therapy; Wound healing

Mesh:

Substances:

Year:  2016        PMID: 27345086     DOI: 10.12968/bjon.2016.25.12.S59

Source DB:  PubMed          Journal:  Br J Nurs        ISSN: 0966-0461


  2 in total

1.  Systematic review of the efficacy of topical haemoglobin therapy for wound healing.

Authors:  Jieman Hu; Shaoning Guo; Haiyan Hu; Jianan Sun
Journal:  Int Wound J       Date:  2020-05-19       Impact factor: 3.315

Review 2.  Update on management of diabetic foot ulcers.

Authors:  Estelle Everett; Nestoras Mathioudakis
Journal:  Ann N Y Acad Sci       Date:  2018-01       Impact factor: 5.691

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.