Literature DB >> 27343121

Blood pressure evaluation and review of antihypertensive medication in patients with life limiting illness.

Felicity Dewhurst1, Lisa Baker1, Inga Andrew1, Adam Todd2.   

Abstract

Background Patients with life limiting illness commonly have multiple co-morbidities that require the use of complex, costly pharmacotherapy. One such example is using medications to treat hypertension in life limiting illness. Objective To: (1) assess the prevalence of previously documented hypertension and associated blood pressure in a cohort of patients with life limiting illness; and, (2) assess the appropriateness of antihypertensive medication in this patient group. Method This was a single centre study at a tertiary, specialist palliative care centre in Northern England. Electronic medical notes were reviewed and data were extracted. Antihypertensive medication was assessed for appropriateness using a conceptual framework. Results A total number of 54 patients were included in the study. Twenty six (48.1 %) had previously documented hypertension: the mean blood pressure of which was 122/65 mmHg (SD 17.0/10.5), while for the normotensive patients it was 122/73 mmHg (SD 21.0/11.6). Of the 26 patients using antihypertensive medication, 25 were assessed as using the medication inappropriately. Conclusions The blood pressure for patients with previously documented hypertension who access specialist palliative care day services is commonly below the NICE target threshold. The majority of these patients are prescribed antihypertensive medications inappropriately.

Entities:  

Keywords:  Deprescribing; Hypertension; Inappropriate medication; Palliative care; United Kingdom

Mesh:

Substances:

Year:  2016        PMID: 27343121     DOI: 10.1007/s11096-016-0327-0

Source DB:  PubMed          Journal:  Int J Clin Pharm


  9 in total

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Review 2.  Falls in older people: epidemiology, risk factors and strategies for prevention.

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Review 3.  Promoting higher blood pressure targets for frail older adults: a consensus guideline from Canada.

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4.  Recommendations to support deprescribing medications late in life.

Authors:  Adam Todd; Holly M Holmes
Journal:  Int J Clin Pharm       Date:  2015-10

5.  Reducing inappropriate polypharmacy: the process of deprescribing.

Authors:  Ian A Scott; Sarah N Hilmer; Emily Reeve; Kathleen Potter; David Le Couteur; Deborah Rigby; Danijela Gnjidic; Christopher B Del Mar; Elizabeth E Roughead; Amy Page; Jesse Jansen; Jennifer H Martin
Journal:  JAMA Intern Med       Date:  2015-05       Impact factor: 21.873

Review 6.  Inappropriate prescribing of preventative medication in patients with life-limiting illness: a systematic review.

Authors:  Adam Todd; Andy Husband; Inga Andrew; Sallie-Anne Pearson; Laura Lindsey; Holly Holmes
Journal:  BMJ Support Palliat Care       Date:  2016-01-05       Impact factor: 3.568

7.  Effect of Discontinuation of Antihypertensive Treatment in Elderly People on Cognitive Functioning--the DANTE Study Leiden: A Randomized Clinical Trial.

Authors:  Justine E F Moonen; Jessica C Foster-Dingley; Wouter de Ruijter; Jeroen van der Grond; Anne Suzanne Bertens; Mark A van Buchem; Jacobijn Gussekloo; Huub A Middelkoop; Marieke J H Wermer; Rudi G J Westendorp; Anton J M de Craen; Roos C van der Mast
Journal:  JAMA Intern Med       Date:  2015-10       Impact factor: 21.873

8.  Symptoms in 400 patients referred to palliative care services: prevalence and patterns.

Authors:  Jean Potter; Faeqa Hami; Tamsin Bryan; Columba Quigley
Journal:  Palliat Med       Date:  2003-06       Impact factor: 4.762

Review 9.  Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies.

Authors:  M R Law; J K Morris; N J Wald
Journal:  BMJ       Date:  2009-05-19
  9 in total
  4 in total

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2.  Missed opportunities: unnecessary medicine use in patients with lung cancer at the end of life - an international cohort study.

Authors:  Adam Todd; Jaafar Al-Khafaji; Nasima Akhter; Adetayo Kasim; Rachel Quibell; Kelly Merriman; Holly M Holmes
Journal:  Br J Clin Pharmacol       Date:  2018-09-22       Impact factor: 4.335

3.  Older Medicare Beneficiaries Frequently Continue Medications with Limited Benefit Following Hospice Admission.

Authors:  Patrick M Zueger; Holly M Holmes; Gregory S Calip; Dima M Qato; A Simon Pickard; Todd A Lee
Journal:  J Gen Intern Med       Date:  2019-07-25       Impact factor: 6.473

4.  Sex-Differences in Discontinuation of Statin Treatment in Cancer Patients the Year before Death.

Authors:  Gabriella Frisk; Helena Bergström; Maria Helde Frankling; Linda Björkhem-Bergman
Journal:  Pharmaceuticals (Basel)       Date:  2021-04-16
  4 in total

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