Literature DB >> 27342232

Research Progress of Natural Product Gentiopicroside - a Secoiridoid Compound.

Shaoping Wu, Yaoyao Ning, Yingyong Zhao, Wenji Sun, Serge Thorimbert, Luc Dechoux, Matthieu Sollogoub, Yongmin Zhang1.   

Abstract

Gentiopicroside is a secoiridoid compound isolated from Gentiana lutea which is called Qin Jiao in Chinese. It is one of the most common herbal medicines used in China. In this article, we review the pharmacological and biological activity (antiviral, anti-inflammatory, analgesia, antihepatotoxic and choleretic), as well as biotransformation of the gentiopicroside. In addition, attempt towards the total synthesis of gentiopicroside is also presented.

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Year:  2017        PMID: 27342232     DOI: 10.2174/1389557516666160624124127

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN: 1389-5575            Impact factor:   3.862


  5 in total

1.  Antiadipogenic Effects of Loganic Acid in 3T3-L1 Preadipocytes and Ovariectomized Mice.

Authors:  Eunkuk Park; Jeonghyun Kim; Subin Yeo; Gijeong Kim; Eun-Hee Ko; Sang Woo Lee; Wan Yi Li; Chun Whan Choi; Seon-Yong Jeong
Journal:  Molecules       Date:  2018-07-09       Impact factor: 4.411

2.  Gentiopicroside targets PAQR3 to activate the PI3K/AKT signaling pathway and ameliorate disordered glucose and lipid metabolism.

Authors:  Haiming Xiao; Xiaohong Sun; Zeyuan Lin; Yan Yang; Meng Zhang; Zhanchi Xu; Peiqing Liu; Zhongqiu Liu; Heqing Huang
Journal:  Acta Pharm Sin B       Date:  2022-01-06       Impact factor: 14.903

Review 3.  Monoterpenes as Sirtuin-1 Activators: Therapeutic Potential in Aging and Related Diseases.

Authors:  Cátia Sousa; Alexandrina Ferreira Mendes
Journal:  Biomolecules       Date:  2022-06-30

4.  Gentiopicroside Ameliorates the Progression from Hepatic Steatosis to Fibrosis Induced by Chronic Alcohol Intake.

Authors:  Hong-Xu Yang; Yue Shang; Quan Jin; Yan-Ling Wu; Jian Liu; Chun-Ying Qiao; Zi-Ying Zhan; Huan Ye; Ji-Xing Nan; Li-Hua Lian
Journal:  Biomol Ther (Seoul)       Date:  2020-07-01       Impact factor: 4.634

5.  Gentiopicroside, a Secoiridoid Glycoside from Gentiana rigescens Franch, Extends the Lifespan of Yeast via Inducing Mitophagy and Antioxidative Stress.

Authors:  Qian Liu; Lihong Cheng; Akira Matsuura; Lan Xiang; Jianhua Qi
Journal:  Oxid Med Cell Longev       Date:  2020-08-02       Impact factor: 6.543

  5 in total

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