Literature DB >> 27340375

An Update on Geriatric Medication Safety and Challenges Specific to the Care of Older Adults.

Michael Koronkowski1, Christine Eisenhower2, Zachary Marcum3.   

Abstract

The prescribing of drug therapies in older adults presents a number of safety challenges. The increased complexity of chronic care for older adults has led to polypharmacy and potentially inappropriate medication use, which can contribute to drug-induced diseases, adverse drug reactions, drug interactions, cognitive impairment, falls, hospitalization, and mortality. In this review, the authors discuss recent medication safety literature pertaining to the classes of medications commonly prescribed to older adults: anticholinergics, psychiatric medications, and antibiotics. Safety concerns associated with the use of these medications and the implications for long-term care practitioners are reviewed. The information provided can be used to inform and improve geriatric care delivered by practitioners across health care environments.

Entities:  

Keywords:  adverse drug events; drug interactions; geriatrics; medication safety; older adults; postmarketing surveillance

Year:  2016        PMID: 27340375      PMCID: PMC4915389     

Source DB:  PubMed          Journal:  Ann Longterm Care        ISSN: 1524-7929


  15 in total

Review 1.  Adverse reactions as a cause of hospital admission in the aged.

Authors:  K Beard
Journal:  Drugs Aging       Date:  1992 Jul-Aug       Impact factor: 3.923

2.  American Geriatrics Society 2015 Updated Beers Criteria for Potentially Inappropriate Medication Use in Older Adults.

Authors: 
Journal:  J Am Geriatr Soc       Date:  2015-10-08       Impact factor: 5.562

3.  Trimethoprim-sulfamethoxazole and risk of sudden death among patients taking spironolactone.

Authors:  Tony Antoniou; Simon Hollands; Erin M Macdonald; Tara Gomes; Muhammad M Mamdani; David N Juurlink
Journal:  CMAJ       Date:  2015-02-02       Impact factor: 8.262

4.  Cumulative use of strong anticholinergics and incident dementia: a prospective cohort study.

Authors:  Shelly L Gray; Melissa L Anderson; Sascha Dublin; Joseph T Hanlon; Rebecca Hubbard; Rod Walker; Onchee Yu; Paul K Crane; Eric B Larson
Journal:  JAMA Intern Med       Date:  2015-03       Impact factor: 21.873

5.  Anticholinergic drug use and risk for dementia: target for dementia prevention.

Authors:  Frank Jessen; Hanna Kaduszkiewicz; Moritz Daerr; Horst Bickel; Michael Pentzek; Steffi Riedel-Heller; Michael Wagner; Siegfried Weyerer; Birgitt Wiese; Hendrik van den Bussche; Karl Broich; Wolfgang Maier
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2010-10-20       Impact factor: 5.270

6.  Renal mechanism of trimethoprim-induced hyperkalemia.

Authors:  H Velázquez; M A Perazella; F S Wright; D H Ellison
Journal:  Ann Intern Med       Date:  1993-08-15       Impact factor: 25.391

7.  Drugs with anticholinergic properties, cognitive decline, and dementia in an elderly general population: the 3-city study.

Authors:  Isabelle Carrière; Annie Fourrier-Reglat; Jean-François Dartigues; Olivier Rouaud; Florence Pasquier; Karen Ritchie; Marie-Laure Ancelin
Journal:  Arch Intern Med       Date:  2009-07-27

8.  Emergency department visits by adults for psychiatric medication adverse events.

Authors:  Lee M Hampton; Matthew Daubresse; Hsien-Yen Chang; G Caleb Alexander; Daniel S Budnitz
Journal:  JAMA Psychiatry       Date:  2014-09       Impact factor: 21.596

Review 9.  STOPP/START criteria for potentially inappropriate prescribing in older people: version 2.

Authors:  Denis O'Mahony; David O'Sullivan; Stephen Byrne; Marie Noelle O'Connor; Cristin Ryan; Paul Gallagher
Journal:  Age Ageing       Date:  2014-10-16       Impact factor: 10.668

10.  Co-trimoxazole and sudden death in patients receiving inhibitors of renin-angiotensin system: population based study.

Authors:  Michael Fralick; Erin M Macdonald; Tara Gomes; Tony Antoniou; Simon Hollands; Muhammad M Mamdani; David N Juurlink
Journal:  BMJ       Date:  2014-10-30
View more
  1 in total

1.  Impact of informed consent content and length on recruitment of older adults into a community based primary prevention trial.

Authors:  Fleur O'Hare; Simone Spark; Zachary Flanagan; Stephane Heritier; Andrea Curtis; Sophia Zoungas
Journal:  Contemp Clin Trials Commun       Date:  2018-06-12
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.