Andreas Anwandter1, Stephanie Bohmann2, Mauricio Nally3, Ana B Castro4, Marc Quirynen5, Nelson Pinto6. 1. Periodontology and Oral Implantology, University of the Andes, Chile. 2. Oral Prosthetic and Surgical Implantology, University of the Andes, Chile. 3. Graduate School of Periodontology and Implant Dentistry, Faculty of Dentistry, University of the Andes, Chile. 4. Department of Oral Health Sciences, KU Leuven & Dentistry, University Hospitals Leuven, Periodontology, Belgium. Electronic address: anabelen.castrosarda@kuleuven.be. 5. Department of Oral Health Sciences, KU Leuven & Dentistry, University Hospitals Leuven, Periodontology, Belgium. 6. Graduate School of Periodontology and Implant Dentistry, Faculty of Dentistry, University of the Andes, Chile; Department of Oral Health Sciences, KU Leuven & Dentistry, University Hospitals Leuven, Periodontology, Belgium.
Abstract
OBJECTIVES: This clinical trial explored the clinical and radiographic dimensional changes of the alveolar ridge in the first 4 months after tooth extraction in combination with the application of Leukocyte- and Platelet Rich Fibrin (L-PRF). METHODS: Eighteen single rooted maxillary and mandibular sockets were filled with L-PRF without soft tissue closure. Clinical measurements (bone sounding) were performed using a customized acrylic stent and radiographic measurements were accomplished using Cone Beam Computed Tomography (CBCT), immediately after tooth extraction and after 4 months. RESULTS: The clinical observations indicated a mean horizontal resorption of 1.18±2.4mm (p=0.8) at the crest, 1.25±2.0mm (p=0.57) and 0.83±2.0mm (p=0.78) at 2mm and 4mm apical to the crest, respectively. The buccal plate demonstrated a mean vertical loss of 0.44±3.5mm (p=0.9), the centre of the socket had a significant filling of 5.72±3.6mm (p=0.0001) and the oral cortical plate had a mean vertical gain of 0.09mm±1.57mm (p=0.9). The radiographic analysis demonstrated a mean vertical bone loss of 0.27±2.5mm (p=0.9) on the buccal and of 0.03±1.6mm (p=0.9) at the oral crest. The width of the alveolar ridge had a mean loss of 1.33mm±1.43mm. CONCLUSIONS: Within the limitations of this pilot study, it can be concluded that L-PRF might show clinical benefits for ridge preservation.
OBJECTIVES: This clinical trial explored the clinical and radiographic dimensional changes of the alveolar ridge in the first 4 months after tooth extraction in combination with the application of Leukocyte- and Platelet Rich Fibrin (L-PRF). METHODS: Eighteen single rooted maxillary and mandibular sockets were filled with L-PRF without soft tissue closure. Clinical measurements (bone sounding) were performed using a customized acrylic stent and radiographic measurements were accomplished using Cone Beam Computed Tomography (CBCT), immediately after tooth extraction and after 4 months. RESULTS: The clinical observations indicated a mean horizontal resorption of 1.18±2.4mm (p=0.8) at the crest, 1.25±2.0mm (p=0.57) and 0.83±2.0mm (p=0.78) at 2mm and 4mm apical to the crest, respectively. The buccal plate demonstrated a mean vertical loss of 0.44±3.5mm (p=0.9), the centre of the socket had a significant filling of 5.72±3.6mm (p=0.0001) and the oral cortical plate had a mean vertical gain of 0.09mm±1.57mm (p=0.9). The radiographic analysis demonstrated a mean vertical bone loss of 0.27±2.5mm (p=0.9) on the buccal and of 0.03±1.6mm (p=0.9) at the oral crest. The width of the alveolar ridge had a mean loss of 1.33mm±1.43mm. CONCLUSIONS: Within the limitations of this pilot study, it can be concluded that L-PRF might show clinical benefits for ridge preservation.
Authors: Vasilena Ivanova; Ivan Chenchev; Stefan Zlatev; Georgi Iordanov; Eitan Mijiritsky Journal: Int J Environ Res Public Health Date: 2019-01-05 Impact factor: 3.390
Authors: João Miguel Santos; Joana A Marques; Margarida Esteves; Vítor Sousa; Paulo J Palma; Sérgio Matos Journal: J Clin Med Date: 2022-08-30 Impact factor: 4.964