David John Saxby1, Adam L Bryant, Luca Modenese, Pauline Gerus, Bryce A Killen, Jason Konrath, Karine Fortin, Tim V Wrigley, Kim L Bennell, Flavia M Cicuttini, Christopher Vertullo, Julian A Feller, Tim Whitehead, Price Gallie, David G Lloyd. 1. 1Innovations in Health Technology, Menzies Health Institute Queensland, Griffith University, Gold Coast, AUSTRALIA; 2Centre for Health, Exercise and Sports Medicine, University of Melbourne, AUSTRALIA; 3Department of Mechanical Engineering, University of Sheffield, UNITED KINGDOM; 4INSIGNEO Institute for In Silico Medicine, University of Sheffield, UNITED KINGDOM; 5Laboratory of Human Motion, Education and Health, University of Nice Sophia-Antipolis, Nice, FRANCE; 6Department of Epidemiology and Preventive Medicine, Monash University, AUSTRALIA; 7Knee Research Australia, AUSTRALIA; 8OrthoSport Victoria, Epworth Richmond, Melbourne, AUSTRALIA; 9College of Science, Health and Engineering, La Trobe University, Melbourne, AUSTRALIA; and 10Coast Orthopaedics, Gold Coast, AUSTRALIA.
Abstract
PURPOSE: To investigate differences in anterior cruciate ligament-reconstructed (ACLR) and healthy individuals in terms of the magnitude of the tibiofemoral contact forces, as well as the relative muscle and external load contributions to those contact forces, during walking, running, and sidestepping gait tasks. METHODS: A computational EMG-driven neuromusculoskeletal model was used to estimate the muscle and tibiofemoral contact forces in those with single-bundle combined semitendinosus and gracilis tendon autograft ACLR (n = 104, 29.7 ± 6.5 yr, 78.1 ± 14.4 kg) and healthy controls (n = 60, 27.5 ± 5.4 yr, 67.8 ± 14.0 kg) during walking (1.4 ± 0.2 m·s), running (4.5 ± 0.5 m·s) and sidestepping (3.7 ± 0.6 m·s). Within the computational model, the semitendinosus of ACLR participants was adjusted to account for literature reported strength deficits and morphological changes subsequent to autograft harvesting. RESULTS: ACLR had smaller maximum total and medial tibiofemoral contact forces (~80% of control values, scaled to bodyweight) during the different gait tasks. Compared with controls, ACLR were found to have a smaller maximum knee flexion moment, which explained the smaller tibiofemoral contact forces. Similarly, compared with controls, ACLR had both a smaller maximum knee flexion angle and knee flexion excursion during running and sidestepping, which may have concentrated the articular contact forces to smaller areas within the tibiofemoral joint. Mean relative muscle and external load contributions to the tibiofemoral contact forces were not significantly different between ACLR and controls. CONCLUSIONS: ACLR had lower bodyweight-scaled tibiofemoral contact forces during walking, running, and sidestepping, likely due to lower knee flexion moments and straighter knee during the different gait tasks. The relative contributions of muscles and external loads to the contact forces were equivalent between groups.
PURPOSE: To investigate differences in anterior cruciate ligament-reconstructed (ACLR) and healthy individuals in terms of the magnitude of the tibiofemoral contact forces, as well as the relative muscle and external load contributions to those contact forces, during walking, running, and sidestepping gait tasks. METHODS: A computational EMG-driven neuromusculoskeletal model was used to estimate the muscle and tibiofemoral contact forces in those with single-bundle combined semitendinosus and gracilis tendon autograft ACLR (n = 104, 29.7 ± 6.5 yr, 78.1 ± 14.4 kg) and healthy controls (n = 60, 27.5 ± 5.4 yr, 67.8 ± 14.0 kg) during walking (1.4 ± 0.2 m·s), running (4.5 ± 0.5 m·s) and sidestepping (3.7 ± 0.6 m·s). Within the computational model, the semitendinosus of ACLR participants was adjusted to account for literature reported strength deficits and morphological changes subsequent to autograft harvesting. RESULTS: ACLR had smaller maximum total and medial tibiofemoral contact forces (~80% of control values, scaled to bodyweight) during the different gait tasks. Compared with controls, ACLR were found to have a smaller maximum knee flexion moment, which explained the smaller tibiofemoral contact forces. Similarly, compared with controls, ACLR had both a smaller maximum knee flexion angle and knee flexion excursion during running and sidestepping, which may have concentrated the articular contact forces to smaller areas within the tibiofemoral joint. Mean relative muscle and external load contributions to the tibiofemoral contact forces were not significantly different between ACLR and controls. CONCLUSIONS: ACLR had lower bodyweight-scaled tibiofemoral contact forces during walking, running, and sidestepping, likely due to lower knee flexion moments and straighter knee during the different gait tasks. The relative contributions of muscles and external loads to the contact forces were equivalent between groups.
Authors: David John Saxby; Adam L Bryant; Ans Van Ginckel; Yuanyuan Wang; Xinyang Wang; Luca Modenese; Pauline Gerus; Jason M Konrath; Karine Fortin; Tim V Wrigley; Kim L Bennell; Flavia M Cicuttini; Christopher Vertullo; Julian A Feller; Tim Whitehead; Price Gallie; David G Lloyd Journal: Knee Surg Sports Traumatol Arthrosc Date: 2018-06-07 Impact factor: 4.342
Authors: Luke G Perraton; Michelle Hall; Ross A Clark; Kay M Crossley; Yong-Hao Pua; Tim S Whitehead; Hayden G Morris; Adam G Culvenor; Adam L Bryant Journal: Knee Surg Sports Traumatol Arthrosc Date: 2017-11-28 Impact factor: 4.342
Authors: Jacob J Capin; Ashutosh Khandha; Ryan Zarzycki; Kurt Manal; Thomas S Buchanan; Lynn Snyder-Mackler Journal: J Orthop Res Date: 2016-11-18 Impact factor: 3.494
Authors: Jacob J Capin; Ryan Zarzycki; Naoaki Ito; Ashutosh Khandha; Celeste Dix; Kurt Manal; Thomas S Buchanan; Lynn Snyder-Mackler Journal: J Orthop Res Date: 2019-05-20 Impact factor: 3.494
Authors: Claudio Pizzolato; Monica Reggiani; David J Saxby; Elena Ceseracciu; Luca Modenese; David G Lloyd Journal: IEEE Trans Neural Syst Rehabil Eng Date: 2017-04-18 Impact factor: 3.802
Authors: Steven Pfeiffer; Matthew S Harkey; Laura E Stanley; J Troy Blackburn; Darin A Padua; Jeffrey T Spang; Stephen W Marshall; Joanne M Jordan; Randy Schmitz; Daniel Nissman; Brian Pietrosimone Journal: Arthritis Care Res (Hoboken) Date: 2018-07-04 Impact factor: 4.794
Authors: H C Davis; B A Luc-Harkey; M K Seeley; J Troy Blackburn; B Pietrosimone Journal: Osteoarthritis Cartilage Date: 2019-01-18 Impact factor: 6.576
Authors: Benoit Pairot-de-Fontenay; Richard W Willy; Audrey R C Elias; Ryan L Mizner; Marc-Olivier Dubé; Jean-Sébastien Roy Journal: Sports Med Date: 2019-09 Impact factor: 11.136