Literature DB >> 27335784

Paradidymis - Fact/Fiction and its Significance.

M Raghavendran1, A Venugopal2, V Ranjit1, Vinay N Kaushik1.   

Abstract

A 30-year old infertile male was admitted for microsurgical sub inguinal varicocelectomy. Intraoperatively, two tubular structures of the caliber of neighboring veins were noted. They were distinct from the vas, which was carefully preserved. Histopathology revealed varicose veins along with two convoluted tubular structures lined by ciliated pseudo-stratified epithelium. There was an incomplete thin muscle coat. The lumina were irregular and contained no spermatozoa (Fig. 1). These structures were identified as paradidymis based on the location in the cord and microscopic morphology. We have tried to analyze the medico-legal significance of these benign lesions in our every day practice.

Entities:  

Keywords:  Mesonephric duct; Paradidymis; Testicular and epididymal appendages; Varicocele; Varicocelectomy; Vas deferens

Year:  2016        PMID: 27335784      PMCID: PMC4909499          DOI: 10.1016/j.eucr.2016.03.013

Source DB:  PubMed          Journal:  Urol Case Rep        ISSN: 2214-4420


Discussion

Testicular/epididymal appendages were once seen only in anatomical books, but are now known to exist in normal individuals (Fig. 1).1, 2 Five appendages are described, namely Appendix Testis, Appendix Epididymis, Cranial and Caudal Haller's organs and Paradidymis or Giralde's organs. Paradidymis are located in the distal portion of spermatic cord. The Appendix Testis is of paramesonephric (Mullerian) duct origin while all other appendages are of mesonephric (Wolffian) duct origin.
Figure 1

Microscopic appearance of paradidymis (P) in the spermatic cord, amidst the dilated veins (V).

The commonly reported problems in the appendages are torsion with a single additional case of tumor reported. As of date, Paradidymis and Haller's organs have not been described to the best of our knowledge. This may be because these structures are usually seen in the cord while the literature is from studies of orchidectomy specimens.1, 2 Hence, paradidymis is an organ of unknown clinical significance. Epididymal appendages are blind ending pedunculated tubular structures with connection to vas. The present case highlights the fact that these can also be seen as completely distinct tubular structures. Hence, identification of paradidymis in surgical specimens (varicocelectomy) is important as it can be mistaken for Vas deferens. Proper identification will help urologists avoid major medico-legal problems in the increasingly commercial and litigant world.

Conflicts of interest

None.
  3 in total

1.  Incidence and structure of the appendices of the testis and epididymis.

Authors:  D Sahni; I Jit; K Joshi
Journal:  J Anat       Date:  1996-10       Impact factor: 2.610

2.  Acute scrotal pain in children: results of 543 surgical explorations.

Authors:  E Van Glabeke; A Khairouni; M Larroquet; G Audry; M Gruner
Journal:  Pediatr Surg Int       Date:  1999-07       Impact factor: 1.827

3.  Study on the incidence of testicular and epididymal appendages in patients with cryptorchidism.

Authors:  Luciano A Favorito; André G L Cavalcante; Marcio A Babinski
Journal:  Int Braz J Urol       Date:  2004 Jan-Feb       Impact factor: 1.541

  3 in total

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