Literature DB >> 27335446

Human Induced Pluripotent Stem Cells as a Platform for Personalized and Precision Cardiovascular Medicine.

Elena Matsa1, John H Ahrens1, Joseph C Wu1.   

Abstract

Human induced pluripotent stem cells (hiPSCs) have revolutionized the field of human disease modeling, with an enormous potential to serve as paradigm shifting platforms for preclinical trials, personalized clinical diagnosis, and drug treatment. In this review, we describe how hiPSCs could transition cardiac healthcare away from simple disease diagnosis to prediction and prevention, bridging the gap between basic and clinical research to bring the best science to every patient.
Copyright © 2016 the American Physiological Society.

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Mesh：

Year:  2016        PMID： 27335446      PMCID： PMC6345246          DOI： 10.1152/physrev.00036.2015

Source DB:  PubMed          Journal:  Physiol Rev        ISSN： 0031-9333            Impact factor:   37.312


  47 in total

1.  Patient-Specific Induced Pluripotent Stem Cell-Based Disease Model for Pathogenesis Studies and Clinical Pharmacotherapy.

Authors:  Yingxin Li; Karim Sallam; Peter J Schwartz; Joseph C Wu
Journal:  Circ Arrhythm Electrophysiol       Date:  2017-06

2.  Inspiration from heart development: Biomimetic development of functional human cardiac organoids.

Authors:  Dylan J Richards; Robert C Coyle; Yu Tan; Jia Jia; Kerri Wong; Katelynn Toomer; Donald R Menick; Ying Mei
Journal:  Biomaterials       Date:  2017-07-12       Impact factor: 12.479

Review 3.  Operationalizing Precision Cardiovascular Medicine: Three Innovations.

Authors:  Jessica J Wang; Jamil A Aboulhosn; Ira S Hofer; Aman Mahajan; Yibin Wang; Thomas M Vondriska
Journal:  Circ Res       Date:  2016-10-14       Impact factor: 17.367

4.  Human induced pluripotent stem cell line with genetically encoded fluorescent voltage indicator generated via CRISPR for action potential assessment post-cardiogenesis.

Authors:  Yao-Hui Sun; Hillary K J Kao; Che-Wei Chang; Alexander Merleev; James L Overton; Dalyir Pretto; Sergey Yechikov; Emanual Maverakis; Nipavan Chiamvimonvat; James W Chan; Deborah K Lieu
Journal:  Stem Cells       Date:  2019-09-30       Impact factor: 6.277

5.  Cardiac subtype characterization using all-optical action potential imaging.

Authors:  Praveen Shukla; Joseph C Wu
Journal:  Eur Heart J       Date:  2017-01-21       Impact factor: 29.983

Review 6.  Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling and Precision Medicine: A Scientific Statement From the American Heart Association.

Authors:  Kiran Musunuru; Farah Sheikh; Rajat M Gupta; Steven R Houser; Kevin O Maher; David J Milan; Andre Terzic; Joseph C Wu
Journal:  Circ Genom Precis Med       Date:  2018-01-12

Review 7.  Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes as Models for Cardiac Channelopathies: A Primer for Non-Electrophysiologists.

Authors:  Priyanka Garg; Vivek Garg; Rajani Shrestha; Michael C Sanguinetti; Timothy J Kamp; Joseph C Wu
Journal:  Circ Res       Date:  2018-07-06       Impact factor: 17.367

8.  Functional correction of dystrophin actin binding domain mutations by genome editing.

Authors:  Viktoriia Kyrychenko; Sergii Kyrychenko; Malte Tiburcy; John M Shelton; Chengzu Long; Jay W Schneider; Wolfram-Hubertus Zimmermann; Rhonda Bassel-Duby; Eric N Olson
Journal:  JCI Insight       Date:  2017-09-21

Review 9.  Personalized Management of Cardiovascular Disorders.

Authors:  Kewal K Jain
Journal:  Med Princ Pract       Date:  2017-09-11       Impact factor: 1.927

Review 10.  Cardiovascular disease models: A game changing paradigm in drug discovery and screening.

Authors:  Houman Savoji; Mohammad Hossein Mohammadi; Naimeh Rafatian; Masood Khaksar Toroghi; Erika Yan Wang; Yimu Zhao; Anastasia Korolj; Samad Ahadian; Milica Radisic
Journal:  Biomaterials       Date:  2018-10-01       Impact factor: 12.479
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