Literature DB >> 27334852

Population-based study shows that resuscitating apparently stillborn extremely preterm babies is associated with poor outcomes.

Morgan Haines1, Ian M Wright2,3, Barbara Bajuk4, Mohamed E Abdel-Latif5,6, Lisa Hilder1, Daniel Challis4, Robert Guaran4, Ju Lee Oei7,8.   

Abstract

AIM: This population-based study determined the delivery room management and outcomes of extremely preterm infants born with Apgar scores of 0.
METHODS: We linked birth, neonatal intensive care unit (NICU) and death records for babies who were born between 22 + 0 and 27 + 6 weeks of gestation with a one-minute Apgar score of 0, in New South Wales, Australia, between 1998 and 2011.
RESULTS: We classified 2173/2262 (96%) of infants with a one-minute Apgar score of 0 as stillborn. Resuscitation was provided for 48/89 (54%) live births and 40/2173 (2%) stillbirths. Cardiac massage was given to 44 infants, including three 22-week stillborn babies. Of the 13 live births admitted to an NICU, 11 survived to hospital discharge. Most (98%) of the 2212 deaths occurred on the first day of life. One baby who was classified as stillborn lived for 51 days. Resuscitation increased the mean (95% confidence interval) duration of survival from 1 (0-2) to 45 (0-104) hours (p < 0.001). No infant with a five-minute Apgar score of 0 survived.
CONCLUSION: Clinicians resuscitated extremely preterm infants without a detectable heartbeat, even at 22 weeks of gestation. No infant survived without resuscitation or if their heartbeat was not regained by five minutes. ©2016 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  Extremely preterm; Mortality; Outcomes; Resuscitation; Stillbirth

Mesh:

Year:  2016        PMID: 27334852     DOI: 10.1111/apa.13503

Source DB:  PubMed          Journal:  Acta Paediatr        ISSN: 0803-5253            Impact factor:   2.299


  2 in total

1.  When Helping Babies Breathe Is Not Enough: Designing a Novel, Mid-Level Neonatal Resuscitation Algorithm for Médecins Sans Frontières Field Teams Working in Low-Resource Hospital Settings.

Authors:  Lisa Umphrey; Morten Breindahl; Alexandra Brown; Ola Didrik Saugstad; Marta Thio; Daniele Trevisanuto; Charles Christoph Roehr; Mats Blennow
Journal:  Neonatology       Date:  2018-05-25       Impact factor: 4.035

Review 2.  [Newborn resuscitation and support of transition of infants at birth].

Authors:  John Madar; Charles C Roehr; Sean Ainsworth; Hege Ersda; Colin Morley; Mario Rüdiger; Christiane Skåre; Tomasz Szczapa; Arjan Te Pas; Daniele Trevisanuto; Berndt Urlesberger; Dominic Wilkinson; Jonathan P Wyllie
Journal:  Notf Rett Med       Date:  2021-06-02       Impact factor: 0.892

  2 in total

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