Literature DB >> 27334043

Epigenetic mechanisms in neurogenesis.

Bing Yao1, Kimberly M Christian2,3, Chuan He4,5, Peng Jin1, Guo-Li Ming2,3,6,7, Hongjun Song2,3,6.   

Abstract

In the embryonic and adult brain, neural stem cells proliferate and give rise to neurons and glia through highly regulated processes. Epigenetic mechanisms - including DNA and histone modifications, as well as regulation by non-coding RNAs - have pivotal roles in different stages of neurogenesis. Aberrant epigenetic regulation also contributes to the pathogenesis of various brain disorders. Here, we review recent advances in our understanding of epigenetic regulation in neurogenesis and its dysregulation in brain disorders, including discussion of newly identified DNA cytosine modifications. We also briefly cover the emerging field of epitranscriptomics, which involves modifications of mRNAs and long non-coding RNAs.

Entities:  

Mesh：

Year:  2016        PMID： 27334043      PMCID： PMC5610421          DOI： 10.1038/nrn.2016.70

Source DB:  PubMed          Journal:  Nat Rev Neurosci        ISSN： 1471-003X            Impact factor:   34.870


  182 in total

1.  MeCP2 binds to non-CG methylated DNA as neurons mature, influencing transcription and the timing of onset for Rett syndrome.

Authors:  Lin Chen; Kaifu Chen; Laura A Lavery; Steven Andrew Baker; Chad A Shaw; Wei Li; Huda Y Zoghbi
Journal:  Proc Natl Acad Sci U S A       Date:  2015-04-13       Impact factor: 11.205

Review 2.  Mechanisms and functional implications of adult neurogenesis.

Authors:  Chunmei Zhao; Wei Deng; Fred H Gage
Journal:  Cell       Date:  2008-02-22       Impact factor: 41.582

3.  m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells.

Authors:  Pedro J Batista; Benoit Molinie; Jinkai Wang; Kun Qu; Jiajing Zhang; Lingjie Li; Donna M Bouley; Ernesto Lujan; Bahareh Haddad; Kaveh Daneshvar; Ava C Carter; Ryan A Flynn; Chan Zhou; Kok-Seong Lim; Peter Dedon; Marius Wernig; Alan C Mullen; Yi Xing; Cosmas C Giallourakis; Howard Y Chang
Journal:  Cell Stem Cell       Date:  2014-10-16       Impact factor: 24.633

4.  Length of huntingtin and its polyglutamine tract influences localization and frequency of intracellular aggregates.

Authors:  D Martindale; A Hackam; A Wieczorek; L Ellerby; C Wellington; K McCutcheon; R Singaraja; P Kazemi-Esfarjani; R Devon; S U Kim; D E Bredesen; F Tufaro; M R Hayden
Journal:  Nat Genet       Date:  1998-02       Impact factor: 38.330

Review 5.  Genetics of Alzheimer's disease.

Authors:  Vincent Chouraki; Sudha Seshadri
Journal:  Adv Genet       Date:  2014       Impact factor: 1.944

6.  MicroRNA cluster miR-17-92 regulates neural stem cell expansion and transition to intermediate progenitors in the developing mouse neocortex.

Authors:  Shan Bian; Janet Hong; Qingsong Li; Laura Schebelle; Andrew Pollock; Jennifer L Knauss; Vidur Garg; Tao Sun
Journal:  Cell Rep       Date:  2013-04-25       Impact factor: 9.423

7.  Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex.

Authors:  João D Pereira; Stephen N Sansom; James Smith; Marc-Werner Dobenecker; Alexander Tarakhovsky; Frederick J Livesey
Journal:  Proc Natl Acad Sci U S A       Date:  2010-08-23       Impact factor: 11.205

8.  Epigenetic regulation of the stem cell mitogen Fgf-2 by Mbd1 in adult neural stem/progenitor cells.

Authors:  Xuekun Li; Basam Z Barkho; Yuping Luo; Richard D Smrt; Nicholas J Santistevan; Changmei Liu; Tomoko Kuwabara; Fred H Gage; Xinyu Zhao
Journal:  J Biol Chem       Date:  2008-08-08       Impact factor: 5.157

9.  Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons.

Authors:  Richard D Smrt; Julialea Eaves-Egenes; Basam Z Barkho; Nicholas J Santistevan; Chunmei Zhao; James B Aimone; Fred H Gage; Xinyu Zhao
Journal:  Neurobiol Dis       Date:  2007-04-27       Impact factor: 5.996

10.  Epigenomic Signatures of Neuronal Diversity in the Mammalian Brain.

Authors:  Alisa Mo; Eran A Mukamel; Fred P Davis; Chongyuan Luo; Gilbert L Henry; Serge Picard; Mark A Urich; Joseph R Nery; Terrence J Sejnowski; Ryan Lister; Sean R Eddy; Joseph R Ecker; Jeremy Nathans
Journal:  Neuron       Date:  2015-06-17       Impact factor: 17.173
View more
  121 in total

1.  Epigenetic dysregulation of Oxtr in Tet1-deficient mice has implications for neuropsychiatric disorders.

Authors:  Aaron J Towers; Martine W Tremblay; Leeyup Chung; Xin-Lei Li; Alexandra L Bey; Wenhao Zhang; Xinyu Cao; Xiaoming Wang; Ping Wang; Lara J Duffney; Stephen K Siecinski; Sonia Xu; Yuna Kim; Xiangyin Kong; Simon Gregory; Wei Xie; Yong-Hui Jiang
Journal:  JCI Insight       Date:  2018-12-06

Review 2.  Regulation of Central Nervous System Development by Class I Histone Deacetylases.

Authors:  Santosh R D'Mello
Journal:  Dev Neurosci       Date:  2020-01-24       Impact factor: 2.984

3.  Epigenetic regulator UHRF1 inactivates REST and growth suppressor gene expression via DNA methylation to promote axon regeneration.

Authors:  Young Mi Oh; Marcus Mahar; Eric E Ewan; Kathleen M Leahy; Guoyan Zhao; Valeria Cavalli
Journal:  Proc Natl Acad Sci U S A       Date:  2018-12-10       Impact factor: 11.205

4.  Fat mass and obesity-associated (FTO) protein regulates adult neurogenesis.

Authors:  Liping Li; Liqun Zang; Feiran Zhang; Junchen Chen; Hui Shen; Liqi Shu; Feng Liang; Chunyue Feng; Deng Chen; Huikang Tao; Tianlei Xu; Ziyi Li; Yunhee Kang; Hao Wu; Lichun Tang; Pumin Zhang; Peng Jin; Qiang Shu; Xuekun Li
Journal:  Hum Mol Genet       Date:  2017-07-01       Impact factor: 6.150

Review 5.  Lens Biology is a Dimension of Neurobiology.

Authors:  Peter Frederikse; Chinnaswamy Kasinathan
Journal:  Neurochem Res       Date:  2017-02-04       Impact factor: 3.996

6.  RB: An essential player in adult neurogenesis.

Authors:  Bensun C Fong; Ruth S Slack
Journal:  Neurogenesis (Austin)       Date:  2017-02-07

7.  An Intrinsic Epigenetic Barrier for Functional Axon Regeneration.

Authors:  Yi-Lan Weng; Ran An; Jessica Cassin; Jessica Joseph; Ruifa Mi; Chen Wang; Chun Zhong; Seung-Gi Jin; Gerd P Pfeifer; Alfonso Bellacosa; Xinzhong Dong; Ahmet Hoke; Zhigang He; Hongjun Song; Guo-Li Ming
Journal:  Neuron       Date:  2017-04-19       Impact factor: 17.173

Review 8.  Gene regulatory mechanisms underlying sex differences in brain development and psychiatric disease.

Authors:  Devanand S Manoli; Jessica Tollkuhn
Journal:  Ann N Y Acad Sci       Date:  2018-01-24       Impact factor: 5.691

Review 9.  Neural stem cell therapies and hypoxic-ischemic brain injury.

Authors:  Lei Huang; Lubo Zhang
Journal:  Prog Neurobiol       Date:  2018-05-21       Impact factor: 11.685

10.  Developmental changes and sex differences in DNA methylation and demethylation in hypothalamic regions of the mouse brain.

Authors:  Carla D Cisternas; Laura R Cortes; Emily C Bruggeman; Bing Yao; Nancy G Forger
Journal:  Epigenetics       Date:  2019-08-03       Impact factor: 4.528
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.